Liposomes as a carrier for 4–hydroxycoumarin: characterisation, stability and antioxidant potential
The aims of the present research were to develop and characterize 4-hydroxycoumarin-loaded liposomes via the determination of encapsulation efficiency, antioxidant capacity, vesicle size, polydispersity index (PDI), zeta potential, conductivity, mobility, density, surface tension, viscosity, and 60-day storage stability. The encapsulation efficien...
By Aleksandra Jovanović, Edina Avdović, Ana Plećić, Vojislav Ćirić, Branko Bugarski, Zoran Marković
Microwawe–assisted extraction of antioxidant compounds from Vaccinium Myrtillus leaves
Vaccinium myrtillus L. (bilberry, Ericaceae), a perennial, wild, and small deciduous shrub that grows in the mountains and forests of Europe. The leaf extracts are widely used in traditional medicine due to their astringent, antiseptic, antioxidant, anti-inflammatory, hypolipidemic, and hypoglycemic activities. Microwave-assisted extraction provide...
By Muna Elferjane, Petar Batinić, Natalija Čutović, Milena Milošević, Vojislav Ćirić, Aleksandar Marinković, Aleksandra Jovanović
Antioxidant, antibacterial and enzyme inhibitory activity of the leaf extracts of Paeonia daurica Andrews wild growing in Serbia
This study was designed to investigate the impact of different extraction methods (ultrasound-assisted extraction, maceration, and microwave-assisted extraction) on the content of polyphenols and biological activities of leaf extract of Paeonia daurica subsp. daurica collected in Južni Kučaj (Serbia). The total polyphenol and flavonoid c...
By Petar Batinic, Natalija Cutovic, Aleksandra Jovanović, Dejan Stojković, Gokhan Zengin, Tamara Carević, Željana Prijić, Aleksandar Marinković, Tatjana Marković
Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes
Steppe peony (Paeonia tenuifolia L., Paeoniaceae) is a perennial, herbaceous plant species which has been widely known for its medicinal use. This study is aimed at the development of P. tenuifolia petal dry methanolic extract-loaded liposomes and the determination of their antioxidant activity. The liposomes were prepared with three different phos...
By Natalija Cutovic, Tatjana Marković, Ana Žugić, Petar Batinic, Branko Bugarski, Aleksandra Jovanović
Natural deep eutectic solvent as tool for improving Rosa canina L. polyphenol recovery in maceration
Rosa canina L. extracts were prepared using water or three natural deep eutectic solvents (NADESs: betaine+malic acid, betaine+sucrose, and citric acid+sucrose with 50% of water) and maceration. The extracts were characterized in terms of total polyphenol content (TPC), ABTS radical scavenging potential, extraction yield, zeta potential, conductivi...
By Aleksandra Jovanović, Rada Pjanović, Jelena Živković, Danica Ćujić, Marija Gnjatović, Sandra Stepanović, Katarina Šavikin
Physicochemical properties of winter savory extracts prepared using ultrasound-assisted extraction
This study aimed to assess the optimal extraction parameters, solvent-to-solid ratio, and extraction time, for ultrasound-assisted extraction of Satureja montana L. (winter savory) harvested from a 6-year-old experimental plantation. The optimization was performed in order to acquire extracts that are rich in the content of polyphenols (TPC), flavo...
By Natalija Čutović, Petar Batinić, Tatjana Marković, Dragoja Radanović, Aleksandar Marinković, Branko Bugarski, Aleksandra Jovanović
The comparison of Ocimum basilicum and Levisticum officinale extracts obtained using different extraction solvents and techniques
In the present study, basil (Ocimum basilicum L.) and lovage (Levisticum officinale Koch.) extracts were obtained using maceration, ultrasound- and microwave-assisted extractions (UAE and MAE, respectively). Varying the different extraction solvents, including water, methanol, acetone, and ethyl acetate, the analyses of total polyphenol and flavono...
By Petar Batinić, Natalija Čutović, Snežana Mrđan, Aleksandra Jovanović, Katarina Čirić, Aleksandar Marinković, Branko Bugarski
Melissa officinalis extracts obtained using maceration, ultrasoundand microwave-assisted extractions: Chemical composition, antioxidant capacity, and physical characteristics
Even though Melissa officinalis L. (lemon balm, fam. Lamiaceae) is a well-known medicinal, aromatic, and spicy plant, and its physicochemical profile and biological activity have been investigated, there is no detailed research regarding the influence of solvent nature (polarity) on the extraction of active compounds (total polyphenols and total fl...
By Aleksandra Jovanović, Milica Mosurović, Branko Bugarski, Petar Batinić, Natalija Čutović, Stefan Gordanić, Tatjana Marković
Ethanol Thymus serpyllum extracts: evaluation of extraction conditions via total polyphenol content and radical scavenging activity
The aim of the present study was the optimization of the extraction conditions (particle size, solid-to-solvent ratio, extraction time and procedure) via total polyphenol content and radical scavenging activity, using wild thyme as a natural source of polyphenols. According to the total polyphenols yield, particle size, solvent-to-solid ratio and e...
By Aleksandra Jovanović, Mihaela Skrt, Predrag Petrović, Gordana Zdunić, Katarina Šavikin, Branko Bugarski
Polyphenols Extraction From Plant Sources
Various conventional (maceration and heat-assisted extraction) and new alternative techniques (ultrasound-assisted extraction and microwave-assisted extraction) have been developed for the extraction of polyphenols compounds from different plant sources. Novel procedures have established with the aim to reduce the extraction time and solvent consum...
By Aleksandra Jovanović, Predrag Petrović, Verica Đorđević, Gordana Zdunić, Katarina Šavikin, Branko Bugarski