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Edited by:

Dr. Milan Lukić

Vol 43, No 1 (2023):

Lekovite Sirovine

Published: 25.12.2023.

Current issue
25.12.2023. Originalan naučni rad– Original scientific paper
Liposomes as a carrier for 4–hydroxycoumarin: characterisation, stability and antioxidant potential

By Aleksandra Jovanović, Edina Avdović, Ana Plećić, Vojislav Ćirić, Branko Bugarski, Zoran Marković

25.12.2023. Originalan naučni rad– Original scientific paper
Microwawe–assisted extraction of antioxidant compounds from Vaccinium Myrtillus leaves

By Muna Elferjane, Petar Batinić, Natalija Čutović, Milena Milošević, Vojislav Ćirić, Aleksandar Marinković, Aleksandra Jovanović

25.12.2023. Pregledni rad – Review Paper
Usage areas, biological activities and volatile oil compounds of Matricaria aurea and Matricaria chamomilla

By Hasan Hüseyin Yaz, İmran Uysal, Abdullah Ozan Polat, Falah Saleh Mohammed, Mustafa Sevindik

25.12.2023. Originalan naučni rad– Original scientific paper
Antioxidant, antibacterial and enzyme inhibitory activity of the leaf extracts of Paeonia daurica Andrews wild growing in Serbia

By Petar Batinic, Natalija Cutovic, Aleksandra Jovanović, Dejan Stojković, Gokhan Zengin, Tamara Carević, Željana Prijić, Aleksandar Marinković, Tatjana Marković

25.12.2023. Originalan naučni rad– Original scientific paper
Apple cider vinegar vs. ethanol as an extraction solvent in the ultrasound-assisted extraction of elderberry fruits

By Zorana Mutavski, Mirjana Sulejmanović, Sladjana Krivošija, Changhui Zhao, Senka Vidović

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27.12.2013. Originalan naučni rad– Original scientific paper

By Sandra Đorđević, Tatjana Marković, Sava Vrbničanin, Dragana Božić

Ambrosia artemisiifolia L. is an allergen species that belongs to the group of invasive weeds, and is very frequent and present in our region. The use of essential oils in the control of weeds attracts great attention of researchers. Many of them have already pointed out the ability of some oils and/or their individual components to delay seed germination of various weeds or completely inhibit it. In this paper, we present results of the efficacy of three essential oils on A. artemisiifolia seeds; the trials were carried out using two different in vitro methods, in which the percentage of seed germination was measured 7th day.  In testings with seeds soaked in essential oil solution, in Petri dishes (500 ml in 100 ml of distilled water), a significant inhibition of germination was observed in the case A. graveolens and S. officinalis oil (100 % and 97 % , respectively), while the oil of S. montana demonstrated slightly weaker inhibitory effect (86 %). When essential oils were applied in form of a vapour (an oil droplet of 25 ml applied on the inner side od Petri dish lids), A. graveolens and S. officinalis oils inhibited the seed germination 100 % and and 95 % , respectively , while the oil of S. montana again demonstrated the weakest inhibitory effect (52 %).

The aim of the presented research was to determine whether the application of the essential oils of A. graveolens, S. officinalis and S. montana in form of a solution or vapor, affects, and to what extent they are important for germination of seeds of the weed species A. artemisiifolia L.

25.12.2017. Research Article
Phytochemical characterization and antioxidant potential of rustyback fern (Asplenium ceterach L.)

By Suzana Živković, Marijana Skorić, Branislav Šiler, Slavica Dmitrović, Biljana Filipović, Tijana Nikolić, Danijela Mišić

25.12.2021. Research Article
Microwave-assisted extraction of essential oil from ginger (Zingiber officinale Rosc.)

By Zorica Drinić, Miloš Jovanović, Dejan Pljevljakušić, Nada Čujić-Nikolić, Dubravka Bigović, Katarina Šavikin

25.12.2021. Research Article
Evaluation of antioxidant activities and haematological effects of Asystasia gangetica leaf extract in monosodium glutamate-treated rats

By Robert Uroko, Amarachi Agbafor, Simeon Egba, Chinedu Nwuke, Sharon Kalu-Kalu

This study evaluated antioxidant activities and haematological effects of methanol extract of Asystasia gangetica leaves (MEAG) on monosodium glutamate (MSG) treated rats. Forty-two male Wistar rats randomly distributed into 7 groups (n=6) were used for the study. Groups 1-3 were the normal control, MSG control, and positive control respectively whereas groups 4-5 were the extract controls, and groups 6-7 were the curative groups. All the treatments were administered orally and standard analytical methods were used for analyses. The results showed that MEAG is a rich antioxidants source and contains phenolics, flavonoids and beta-carotene in high concentrations. The extract showed concentration-dependent increases in ferric reducing antioxidant power, DPPH (2,2-diphenyl-1-picrylhydrazyl) and nitric oxide radicals scavenging activities but relatively lower than their respective controls. The MSG administration caused significant (P<0.05) reductions in the glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT) activities but significantly (P<0.05) increased the malondialdehyde (MDA) concentrations in the MSG control rats. The MSG administration also caused significant (P<0.05) reductions in the haemoglobin (Hb) concentration, packed cell volume (PCV), red blood cell (RBC) and white blood cell (WBC) counts of the MSG control relative to the normal control. Treatment with MEAG significantly elevated GPx, SOD, and CAT activities; haematological indices and significantly reduced MDA levels in the extract controls, and curative groups treated with a high dose of MSG. These findings show that methanol extract of A. gangetica leaves is rich in antioxidants that could prevent oxidative stress and improves the haematological profile of MSG treated rats.


25.12.2021. Research Article
Evaluation of different solvents for phytochemical constituents and antioxidant activities of the leaves of Acanthus montanus (Nees) T. Anderson

By Ale Joy Enitan, Lawal Ibraheem Oduola, Omogbene Temitope Olorunyomi

31.12.2013. Originalan naučni rad– Original scientific paper
SEED QUALITY AND SWELLING INDEX OF MARSHMALLOW (Althaea officinalis L.), LINSEED (Linum usitatissimum L.) AND FENUGREEK (Trigonella foenum graecum L.) SEED

By Vladimir Filipović, Vera Popović, Đorđe Glamočlija, Tatjana Marković, Dragoja Radanović, Vladan Ugrenović, Violeta Mickovski Stefanović

25.12.2018. Research Article
Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L.

By Zorica Drinić, Senka Vidović, Jelena Vladić, Anamarija Koren, Biljana Kiprovski, Vladmir Sikora

25.12.2021. Research Article
Qualitative and quantitative phytochemical evaluation of Quassia undulata (Guill. & Perr.) D. Dietr. leaves using different solvent polarities

By Ibraheem Oduola-Lawal, Adeniyi Olufunso, Ariwoola Oluwole

This study investigated solvent effects on the phytochemical composition of Quassia undulata leaves a medicinal plant used in treating arrays of diseases including fever and cough. The leaves were collected, washed, air-dried, pulverized and evaluated for some inherent phytochemicals using four different solvent systems based on their polarities. The solvents are methanol, acetone, ethyl acetate and chloroform. The methanol extract was found to have the highest number of secondary metabolites (saponins, tannins, flavonoids, steroids, coumarins, anthraquinones, alkaloids and phenols). None of the extracts tested positive for the presence of phlobatannins, terpenoids and emodins. The methanol extract was further analyzed quantitatively for some of the determined phytochemicals. Tannins had a concentration of 3.131 mg of catechin equivalents per 100 mg sample (mg CE/100g), alkaloids - 5.200 %, total phenolics - 11.828 mg of gallic acid equivalents per gram of extract (mg GAE/g), flavonoids - 8.074 mg of quercetin equivalents per gram of extract (mg QE/g) while 0.673 % saponins were detected. The presence of these secondary metabolites might justify the ethnomedicinal uses of Quassia undulata leaves as their bioactivity has been found to be dependent on the solvent used for extraction.


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