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University of Belgrade, Faculty of Biology, Studentski trg 26 , 11 000 Belgrade , Serbia
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University of Belgrade, Faculty of Biology, Studentski trg 26 , 11 000 Belgrade , Serbia
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University of Belgrade, Institute for Biological Research “Siniša Stanković”, - National Institute of Republic of Serbia, Bulevar despota Stefana 142 , 11 000 Belgrade , Serbia
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University of Belgrade, Institute for Biological Research “Siniša Stanković”, - National Institute of Republic of Serbia, Bulevar despota Stefana 142 , 11 000 Belgrade , Serbia
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Institute for Oncology and Radiology of Serbia, Pasterova 14 , 11 000 Belgrade , Serbia
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Institute of Marine Biology, put I Bokeljske brigade 68 , 85330 Kotor , Montenegro
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University of Belgrade, Faculty of Biology, Studentski trg 26 , 11 000 Belgrade , Serbia
University of Belgrade, Institute of Chemistry, Technology and Metallurgy, - National Institute of Republic of Serbia, Department of Chemistry, Njegoševa 12 , 11 000 Belgrade , Serbia
In this study, the antioxidant, antimicrobial, and cytotoxic activities of Codium bursa, Codium effusum, Laurencia obtusa and Padina pavonica from the Adriatic Sea were investigated. The antioxidant activities were characterized by the DPPH (1,1-diphenyl-2-picrylhydrazyl) method and their total phenolic and flavonoid contents were quantified. The antimicrobial activity of four species against 8 pathogenic bacteria: Staphylococcus aureus, Bacillus cereus, Micrococcus luteus, Listeria monocytogenes, Pseudomonas aeruginosa, Salmonella Typhimurium, Escherichia coli, Enterobacter cloacae and 8 fungi: Aspergillus fumigatus, Aspergillus versicolor, Aspergillus ochraceus, Aspergillus niger, Trichoderma viride, Penicillium funiculosum, Penicillium ochrochloron and Penicillium verrucosum var. cyclopium) were used. The antitumor activities were determined using two different tumor cell lines (HeLa and K562). The results have shown potential antioxidant activity of Padina pavonica, antibacterial and antifungal activity of Codium effusum, and strong cytotoxic activity of Laurencia obtusa.
This work was financially supported by Ministri of Science, Technological Development and Innovation of the Republic of Serbia (Grants No., 451-03-65/2024-03/200178, 451-03-66/2024-03/200178, 451-03-66/2024-03/ 200007, 451-03-66/2024-03/200026 and 451-03-66/2024-03/200043).
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