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Vol 40(2020)

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Authors in this issue:

Temilola Akinkunbed, Samuel Bankole, Paul Ogunbamwo, Olamilekan Awotedu, Dejan Pljevljakušić, Sreta Brkić, Senka Vidović, Siniša Simić, Aleksandra Gavarić, MIlica Aćimović, Jelena Vladić, Marija Marković, Biljana Nikolić, Ljubinko Rakonjac, Vesna Stankov-Jovanović, Zorica Drinić, Jelena Mudrić, Mirjana Pajić, Dubravka Bigović, Jelena Đuriš, Miloš Jovanović, Ana Alimpić-Aradski, Sonja Duletić-Laušević, Katarina Šavikin, Stevan Samardžić, Aleksandra Tucović, Danilo Stojanović, Zoran Maksimović, Marina Kostić, Marija Ivanov, Dejan Stojković, Ana Ćirić, Marina Soković, Jovana Stankov-Jovanović, Miroslav Novaković, Vele Tešević, Gordana Zdunić, Zora Dajić Stevanović, Dejan Gođevac, Vanja Tadić, Nemanja Krgović, Ana Žugić, Mirjana Cvetković,

Published: 25.12.2020.

Contents

25.12.2020. Research Article
Antifungal activity of aqueous and corn steep liquor extract of Ficus exasperata, Anonna muricata and Azadiractha indica

This study investigated the activity of aqueous and corn steep liquor (CSL) extracts of Ficus exaperasta, Azadirachta indica and Annona muricata against Candida spp isolated from high vagina swab samples. Phytochemical screening of the plants was done using standard methods, the antifungal activity of the plant’s extracts and standard drugs w...

By TEMILOLA AKINKUNBED, SAMUEL BANKOLE, PAUL OGUNBAMWO, OLAMILEKAN AWOTEDU

25.12.2020. Research Article
Cultivation cost-benefit analysis of some important medicinal plants in Serbia

Driven by frequent media misinformation about the level of profitability of growing certain medicinal plants, in this paper we presented a cost-benefit analysis based on twenty years of experience in field production. The observed costs and profits for peppermint, chamomile, lemon balm, marshmallow, valerian and pot marigold are based on the averag...

By DEJAN PLJEVLJAKUŠIĆ, SRETA BRKIĆ

25.12.2020. Research Article
Extraction of sweet wormwood (Artemisia annua L.) by supercritical carbon dioxide

In this study, supercritical carbon dioxide was applied for the extraction of Artemisia annua L. Moreover, the impact of different parameters of supercritical extraction on total yield was investigated and the obtained yields were compared to the ones obtained by conventional procedures, hydrodistillation and Soxhlet extraction. Supercritical fluid...

By SENKA VIDOVIĆ, SINIŠA SIMIĆ, ALEKSANDRA GAVARIĆ, MILICA AĆIMOVIĆ, JELENA VLADIĆ

25.12.2020. Research Article
Ethnomedicinal application of species from genus Thymus in the Pirot County (Southeastern Serbia)

The species from genus Thymus are polymorphous plants from the family Lamiaceae, spread in Serbia in many species, subspecies, varieties, and forms. The aerial parts of species from genus Thymus have a long tradition of being used worldwide. The subject of this study was the research of ethnomedicinal application of thyme in Pirot County (Southeast...

By MARIJA MARKOVIĆ, DEJAN PLJEVLJAKUŠIĆ, BILJANA NIKOLIĆ, LJUBINKO RAKONJAC, VESNA STANKOV-JOVANOVIĆ

25.12.2020. Research Article
GC/MS chemical analysis of lavandin (Lavandula x intermedia) hydrolat: successive extraction fractions

Hydrolats are valuable co-products of the essential oil distillation process, whose volatile compounds can be quantified by various methods. In this paper, we have tried to estimate the liquid-liquid extraction cycle number threshold for volatile compounds quantification of lavandin (Lavandula x intermedia) hydrolat. For this purpose, ten consecuti...

By DEJAN PLJEVLJAKUŠIĆ, ZORICA DRINIĆ

25.12.2020. Research Article
Development of gastroretentive floating granules with gentian root extract by hot-melt granulation

The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of the solid pharmaceutical forms. Gentiopicroside, as a dominant secoiridoid in the GRE, has a sho...

By JELENA MUDRIĆ, MIRJANA PAJIĆ, DUBRAVKA BIGOVIĆ, JELENA ĐURIŠ

25.12.2020. Research Article
In vitro and in silico prediction of antineurodegenerative properties of Helichrysum plicatum flower extract

This study aimed to assess the antineurodegenerative and antioxidant activity of Helichrysum plicatum flower extract, as well as to identify extract ingredients with acceptable pharmacokinetic parameters such as gastrointestinal absorption, blood-brain barrier permeation, and P-glycoprotein-mediated effusion for optimal therapeutic brain exposure. ...

By MILOŠ JOVANOVIĆ, ZORICA DRINIĆ, DUBRAVKA BIGOVIĆ, ANA ALIMPIĆ-ARADSKI, SONJA DULETIĆ-LAUŠEVIĆ, KATARINA ŠAVIKIN

25.12.2020. Research Article
Isolation and seasonal variation of fruticin in fruits of false indigo-bush (Amorpha fruticosa L. Fabaceae) from Serbia

Fruticin (amorphin) is a constituent of the fruit of the false indigo-bush (Amorpha fruticosa L.), which belongs to the class of rotenoid glycosides, and shows several interesting pharmacological activities. The aim of this study was to isolate and chemically characterize this natural product, as well as to determine the optimal period of the year ...

By STEVAN SAMARDŽIĆ, ALEKSANDRA TUCOVIĆ, DANILO STOJANOVIĆ, ZORAN MAKSIMOVIĆ

25.12.2020. Research Article
Antibacterial and antibiofilm activity of selected polyphenolic compounds: An in vitro study on Staphylococcus aureus

Staphylococcus aureus is a human pathogen that causes serious infections with high mortality rates. The antimicrobial activities of eight phenolic compounds (caffeic acid, chlorogenic acid, ferulic acid, morin, quercetin, isoquercitrin, rutin and hesperidin) were evaluated against planktonic and biofilm forming Staphylococcus aureus cells. Their ab...

By MARINA KOSTIĆ, MARIJA IVANOV, DEJAN STOJKOVIĆ, ANA ĆIRIĆ, MARINA SOKOVIĆ

25.12.2020. Research Article
Antifungal activity of the essential oil from Artemisia santonicum and its constituent isogeranic acid

This study represents a continuation of exploring of the biological activities of the Artemisia santonicum essential oil. The previous investigation was focused on the antibacterial, antibiofilm, and antiquorum activities of A. santonicum essential oil and isogeranic acid as the main antibacterial constituent. The present study describes their anti...

By JOVANA STANKOV-JOVANOVIĆ, MIROSLAV NOVAKOVIĆ, MIROSLAV NOVAKOVIĆ, VELE TEŠEVIĆ, GORDANA ZDUNIĆ, ZORA DAJIĆ STEVANOVIĆ, DEJAN GOĐEVAC

25.12.2020. Review Article
Lady’s mantle (Alchemilla vulgaris L., Rosaceae): A review of traditional uses, phytochemical profile, and biological properties

Lady’s mantle (Alchemilla vulgaris L. syn. Alchemilla xanthochlora Rothm., Rosaceae) has been commonly used in folk medicine to heal inflammations in the mouth, bleeding of the nose, furuncules, gynaecological (menorrhagia and dysmenorrhoea), and gastrointestinal disorders. Although therapeutic indications for Lady’s mantle are non-specific diarrho...

By VANJA TADIĆ, NEMANJA KRGOVIĆ, ANA ŽUGIĆ

25.12.2020. Review Article
Phyto-pharmacological aspects of Nepeta nuda L.: A systematic review

Nepeta nuda L. (syn. N. pannonica L.) is a herbaceous perennial plant, is the most widespread species of the genus Nepeta, the largest genera in Lamiaceae family. However, N. nuda is well spread worldwide, and divided into four subspecies according to morphological differences which occur within large geographical range of distribution: subsp. nuda...

By MILICA AĆIMOVIĆ, JOVANA STANKOV-JOVANOVIĆ, MIRJANA CVETKOVIĆ

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