The microbiological stability of cosmetic products is crucial, especially in products with high water content, such as creams. Therefore, preservatives are used in order to protect consumers from harmful pathogens that would otherwise invade the cosmetics. Despite their function, the addition of preservatives can be considered controversial in the ...

By Tatjana Stević, Nemanja Krgovic, Jelena Mudrić, Nada Cujic Nikolic, Ana Žugić, Dubravka Bigović, Tea Ganić, Katarina Šavikin

Rosa canina L. extracts were prepared using water or three natural deep eutectic solvents (NADESs: betaine+malic acid, betaine+sucrose, and citric acid+sucrose with 50% of water) and maceration. The extracts were characterized in terms of total polyphenol content (TPC), ABTS radical scavenging potential, extraction yield, zeta potential, conductivi...

By Aleksandra Jovanović, Rada Pjanović, Jelena Živković, Danica Ćujić, Marija Gnjatović, Sandra Stepanović, Katarina Šavikin

In this study, the ethnobotanical use of medicinal plants in the rural areas of Osijek-Baranja County, Eastern Republic of Croatia, was analyzed by conducting an ethnobotanical survey with 200 informants. Our aim was to collect and identify plant species used for therapeutic purposes and to record information on traditional herbal medicine. Accordi...

By Smiljana Solarov, Gorana Eljuga, Milan Ilić, Jelena Živković, Nataša Jovanović-Lješković, Katarina Šavikin

Comparison between conventional and microwave-assisted hydrodistillation at different power levels has been applied for the extraction of essential oil from Zingiber officinale Rosc. rhizome. In addition to the collected essential oils, as the main products, hydrolats were also collected, as valuable by-products from both extraction techniques. A c...

By Zorica Drinić, Miloš Jovanović, Dejan Pljevljakušić, Nada Čujić-Nikolić, Dubravka Bigović, Katarina Šavikin

Willowherb (Epilobium angustifolium L.) leaves are a valuable source of polyphenolic compounds (phenolic acids, flavonoids, and ellagitannins) that are mainly used in the treatment of benign prostatic hyperplasia. In the presented study, the impacts of maltodextrin and whey protein as carriers on the efficiency of spray drying and physicochemical p...

By Miloš Janković, Zorica Drinić, Dubravka Bigović, Gordana Zdunić, Jelena Mudrić, Katarina Šavikin

This study aimed to assess the antineurodegenerative and antioxidant activity of Helichrysum plicatum flower extract, as well as to identify extract ingredients with acceptable pharmacokinetic parameters such as gastrointestinal absorption, blood-brain barrier permeation, and P-glycoprotein-mediated effusion for optimal therapeutic brain exposure. ...

By Miloš Jovanović, Zorica Drinić, Dubravka Bigović, Ana Alimpić-Aradski, Sonja Duletić-Laušević, Katarina Šavikin

The aim of the present study was the optimization of the extraction conditions (particle size, solid-to-solvent ratio, extraction time and procedure) via total polyphenol content and radical scavenging activity, using wild thyme as a natural source of polyphenols. According to the total polyphenols yield, particle size, solvent-to-solid ratio and e...

By Aleksandra Jovanović, Mihaela Skrt, Predrag Petrović, Gordana Zdunić, Katarina Šavikin, Branko Bugarski

The stability of linseed (Linum usitatissimum) oil has been investigated through the exposition of two different samples, linseed oil without antioxidant and linseed oil with roesemary (Rosmarinus officinalis) extract, to ambient temperature conditions (25 °C) and refrigerator temperature conditions (4 °C). The oxidation degree of linseed oi...

By Zorica Drinić, Jelena Mudrić, Gordana Zdunić, Dubravka Bigović, Katarina Šavikin

This article describes the preparation, characterization, and application of W/O/W emulsions, with emphasis on the encapsulation of plant bioactives. The main limitations preventing commercialization of double emulsions with plant bioactive substances, used for the preparation of food, nutraceuticals and pharmaceuticals for oral administration, are...

By Jelena Mudrić, Katarina Šavikin, Svetlana Ibrić, Jelena Đuriš

Biological activities of Sorbus aucuparia L. leaves extract was tested in our study. Antineurodegenerative activity was evaluated by acetylcholinesterase (AChE) and tyrosinase (TYR) inhibitory activity assays while antioxidant activity was by tested using four different assays. In all antioxidant test we noticed concentration dependent activity of ...

By Katarina Šavikin, Gordan Zdunić, Ana Alimpić, Dubravka Bigović, Dejan Pljevljakušić, Sonja Duletić-Laušević