Effect of carrier type on the spray-dried willowherb (Epilobium angustifolium L.) leaves extract, powder properties and bioactive compounds encapsulation
Willowherb (Epilobium angustifolium L.) leaves are a valuable source of polyphenolic compounds (phenolic acids, flavonoids, and ellagitannins) that are mainly used in the treatment of benign prostatic hyperplasia. In the presented study, the impacts of maltodextrin and whey protein as carriers on the efficiency of spray drying and physicochemical properties of the obtained powders were examined. The use of carriers significantly improved the drying yield (over 60 %). Moisture content, hygroscopicity, and rehydration time of all dried extracts (without the carrier, with maltodextrin and whey protein) were at an acceptable level, while their flowability and cohesiveness were poor. The encapsulation efficiency of polyphenols in a whey protein carrier of 92.02 % was significantly higher compared to 75.80 % for maltodextrin. These results show that whey protein efficiently encloses the extract ingredients into powder particles and thus preserves sensitive phenolic compounds during the drying process. The efficacy of flavonoid encapsulation was also high (93.00 % for maltodextrin and 94.34 % for whey protein), with no statistically significant differences between carrier types. Therefore, willowherb leaves extract can be successfully encapsulated by spray drying using maltodextrin and whey protein as carriers.
Bakowska-Barczak, A. M., & Kolodziejczyk, P. P. (2011). Black currant polyphenols: Their storage stability and microencapsulation. Industrial Crops and Products, 34(2), 1301–1309. https://doi.org/10.1016/j.indcrop.2010.10.002.
Ballesteros, L. F., Ramirez, M. J., Orrego, C. E., Teixeira, J. A., & Mussatto, S. I. (2017). Encapsulation of antioxidant phenolic compounds extracted from spent coffee grounds by freeze-drying and spray-drying using different coating materials. Food Chemistry, 237, 623–631.
Cai, Y. Z., & Corke, H. (2000). Production and properties of spray dried Amaranthus Betacyanin pigments. Journal of Food Science, 65, 1248–1252. https://doi.org/10.1111/j.13652621.2000.tb10273.x.
Caliskan, G., & Nur Dirim, S. (2015). The effect of different drying processes and the amounts of maltodextrin addition on the powder properties of sumac extract powder. Powder Technology, 287, 308–314. https://doi.org/10.1016/j.powtec.2015.10.019.
Carr, R. L. (1965). Evaluating flow properties of solids. Chemical Engineering, 72, 163–168.
Chaumun, M., Goëlo, V., Ribeiro, A. M., Rocha, F., & Estevinho, B. N. (2020). In vitro evaluation of microparticles with Laurus nobilis L. extract prepared by spray-drying for application in food and pharmaceutical products. Food and Bioproducts Processing, 122, 124–135. https://doi.org/10.1016/j.fbp.2020.04.011.
Ćujić Nikolić, N., Stanisavljevič, N., Šavikin, K., Kalušević, A., Nedović, V., Bigović, D., & Janković, T. (2018). Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method. Lekovite Sirovine, 38, 9–16. https://doi.org/10.1364/leksir1838009C.
Díaz-Bandera, D., Villanueva-Carvajal, A., Dublán-García, O., Quintero-Salazar, B., & Dominguez-Lopez, A. (2015). Assessing release kinetics and dissolution of spray-dried Roselle (Hibiscus sabdariffa L.) extract encapsulated with different carrier agents. LWT - Food Science and Technology, 64(2), 693–698. https://doi.org/10.1016/j.lwt.2015.06.047.
Esposito, C., Santarcangelo, C., Masselli, R., Buonomo, G., Nicotra, G., Insolia, V., D’Avino, M., Caruso, G., Buonomo, A. R., Sacchi, R., Sommella, E., Campiglia, P., Tenore, G. C., & Daglia, M. (2021). Epilobium angustifolium L. extract with high content in oenothein B on benign prostatic hyperplasia: A monocentric, randomized, double-blind, placebo-controlled clinical trial. Biomedicine and Pharmacotherapy, 138, 111414.
Goula, A. M., & Adamopoulos, K. G. (2010). A new technique for spray drying orange juice concentrate. Innovative Food Science and Emerging Technologies, 11(2), 342–351. https://doi.org/10.1016/j.ifset.2009.12.001.
Granica, S., Piwowarski, J. P., Czerwińska, M. E., & Kiss, A. K. (2014). Phytochemistry, pharmacology and traditional uses of different Epilobium species (Onagraceae): a review. Journal of Ethnopharmacology, 156, 316–346.
Hausner, H. H. (1967). Friction conditions in a mass of metal powder. International Journal of Powder Metallurgy, 3(4), 7–13.
Hevesi Tóth, B., Blazics, B., & Kéry, A. (2009). Polyphenol composition and antioxidant capacity of Epilobium species. Journal of Pharmaceutical and Biomedical Analysis, 49(1), 26–31.
Hogekamp, S., & Schubert, H. (2003). Rehydration of Food Powders. Food Science and Technology International, 9(3), 223–235.
Jinapong, N., Suphantharika, M., & Jamnong, P. (2008). Production of instant soymilk powders by ultrafiltration, spray drying and fluidized bed agglomeration. Journal of Food Engineering, 84, 194–205.
Loizzo, M., Tundis, R., Bonesi, M., Menichini, F., Mastellone, V., Avallone, L., & Menichini, F. (2012). Radical scavenging, antioxidant and metal chelating activities of Annona cherimola Mill. (cherimoya) peel and pulp in relation to their total phenolic and total flavonoid contents. Journal of Food Composition and Analysis, 25, 179–184. https://doi.org/10.1016/j.jfca.2011.09.002.
Mahdi, A. A., Mohammed, J. K., Al-Ansi, W., Ghaleb, A. D. S., Al-Maqtari, Q. A., Ma, M., Ahmed, M. I., & Wang, H. (2020). Microencapsulation of fingered citron extract with gum arabic, modified starch, whey protein, and maltodextrin using spray drying. International Journal of Biological Macromolecules, 152, 1125–1134.
Morais, F. P. R., Pessato, T. B., Rodrigues, E., Mallmann, L. P., Mariutti, L. R. B., & Netto, F. (2020). Whey protein and phenolic compound complexation: Effects on antioxidant capacity before and after in vitro digestion. Food Research International, 133, 109104. https://doi.org/10.1016/j.foodres.2020.109104.
Schepetkin, I. A., Ramstead, A. G., Kirpotina, L. N., Voyich, J. M., Jutila, M. A., & Quinn, M. T. (2016). Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed. Phytotherapy Research, 30(8), 1287–1297.
Shikov, A. N., Poltanov, E. A., Dorman, H. J., Makarov, V. G., Tikhonov, V. P., & Hiltunen, R. (2006). Chemical composition and in vitro antioxidant evaluation of commercial water-soluble willow herb (Epilobium angustifolium L.) extracts. Journal of Agricultural and Food Chemistry, 54(10), 3617–3624.
Sõukand, R., Mattalia, G., Kolosova, V., Stryamets, N., Prakofjewa, J., Belichenko, O., Kuznetsova, N., Minuzzi, S., Keedus, L., Prūse, B., Simanova, A., Ippolitova, A., & Kalle, R. (2020). Inventing a herbal tradition: The complex roots of the current popularity of Epilobium angustifolium in Eastern Europe. Journal of Ethnopharmacology, 247, 112254.
Stolarczyk, M., Piwowarski, J. P., Granica, S., Stefańska, J., Naruszewicz, M., & Kiss, A. K. (2013). Extracts from Epilobium sp. herbs, their components and gut microbiota metabolites of Epilobium ellagitannins, urolithins, inhibit hormone-dependent prostate cancer cells-(LNCaP) proliferation and PSA secretion. Phytotherapy Research, 27(12), 1842–1848.
Tontul, I., & Topuz, A. (2017). Spray-drying of fruit and vegetable juices: Effect of drying conditions on the product yield and physical properties. Trends in Food Science and Technology, 63, 91–102. https://doi.org/10.1016/j.tifs.2017.03.009.
Vidović, S. S., Vladić, J. Z., Vaštag, Ž. G., Zeković, Z. P., & Popović, L. M. (2014). Maltodextrin as a carrier of health benefit compounds in Satureja montana dry powder extract obtained by spray drying technique. Powder Technology, 258, 209–215. https://doi.org/10.1016/j.powtec.2014.03.038.
Waterman, P. G., & Mole, S. (1994). Analysis of phenolic plant metabolites. Blackwell Scientific Publication, Oxford.
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