Liposomes as a carrier for 4–hydroxycoumarin: characterisation, stability and antioxidant potential
The aims of the present research were to develop and characterize 4-hydroxycoumarin-loaded liposomes via the determination of encapsulation efficiency, antioxidant capacity, vesicle size, polydispersity index (PDI), zeta potential, conductivity, mobility, density, surface tension, viscosity, and 60-day storage stability. The encapsulation efficien...
By Aleksandra Jovanović, Edina Avdović, Ana Plećić, Vojislav Ćirić, Branko Bugarski, Zoran Marković
Microwawe–assisted extraction of antioxidant compounds from Vaccinium Myrtillus leaves
Vaccinium myrtillus L. (bilberry, Ericaceae), a perennial, wild, and small deciduous shrub that grows in the mountains and forests of Europe. The leaf extracts are widely used in traditional medicine due to their astringent, antiseptic, antioxidant, anti-inflammatory, hypolipidemic, and hypoglycemic activities. Microwave-assisted extraction provide...
By Muna Elferjane, Petar Batinić, Natalija Čutović, Milena Milošević, Vojislav Ćirić, Aleksandar Marinković, Aleksandra Jovanović
Usage areas, biological activities and volatile oil compounds of Matricaria aurea and Matricaria chamomilla
Plants are natural products responsible for many biological activities. It is quite common to use plants that attract attention with their nutritive properties within the scope of complementary medicine. Matricaria species, which have naturally distributed, are among the plants used in traditional medicine. Revealing the biological activities of p...
By Hasan Hüseyin Yaz, İmran Uysal, Abdullah Ozan Polat, Falah Saleh Mohammed, Mustafa Sevindik
Antioxidant, antibacterial and enzyme inhibitory activity of the leaf extracts of Paeonia daurica Andrews wild growing in Serbia
This study was designed to investigate the impact of different extraction methods (ultrasound-assisted extraction, maceration, and microwave-assisted extraction) on the content of polyphenols and biological activities of leaf extract of Paeonia daurica subsp. daurica collected in Južni Kučaj (Serbia). The total polyphenol and flavonoid c...
By Petar Batinic, Natalija Cutovic, Aleksandra Jovanović, Dejan Stojković, Gokhan Zengin, Tamara Carević, Željana Prijić, Aleksandar Marinković, Tatjana Marković
Apple cider vinegar vs. ethanol as an extraction solvent in the ultrasound-assisted extraction of elderberry fruits
Traditional plant extraction methods commonly employ hazardous solvents that threaten human health. Considering these, the study sought to explore the efficacy of seven distinct types of apple cider vinegar (ACV) as an alternative solvent for isolating polyphenols from dry elderberries as a raw material. In the pursuit of identifying the most suita...
By Zorana Mutavski, Mirjana Sulejmanović, Sladjana Krivošija, Changhui Zhao, Senka Vidović
Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes
Steppe peony (Paeonia tenuifolia L., Paeoniaceae) is a perennial, herbaceous plant species which has been widely known for its medicinal use. This study is aimed at the development of P. tenuifolia petal dry methanolic extract-loaded liposomes and the determination of their antioxidant activity. The liposomes were prepared with three different phos...
By Natalija Cutovic, Tatjana Marković, Ana Žugić, Petar Batinic, Branko Bugarski, Aleksandra Jovanović
Developed and validated HPLC method for simultaneous analysis of key flavonoids and phenolcarboxylic acids in the hawthorn-based cardiotonic Forticor®
Relatively simple, but very reliable, one-step qualitative/quantitative HPLC analysis of four key flavonoids, and a phenolcarboxylic acid, has been introduced. For substrate/sample preparations, either triple percolations, using 70% ethanol-water (V/V), or/and ultrasonic bath methanol extractions, were carried out to obtain the desired isolates yi...
By Vanja Tadic, Dragica Bojovic, Goran Marković, Ivana Nešić, Ana Žugić
Microbiological quality and efficacy of preservatives in marigold-based skin care products
The microbiological stability of cosmetic products is crucial, especially in products with high water content, such as creams. Therefore, preservatives are used in order to protect consumers from harmful pathogens that would otherwise invade the cosmetics. Despite their function, the addition of preservatives can be considered controversial in the ...
By Tatjana Stević, Nemanja Krgovic, Jelena Mudrić, Nada Cujic Nikolic, Ana Žugić, Dubravka Bigović, Tea Ganić, Katarina Šavikin
Antimicrobial activity of Hyssopus officinalis L. subsp. aristatus (Godr.) Nyman (Lamiaceae) essential oils from Montenegro and Serbia
In this study, antimicrobial activity of essential oils extracted from the aerial flowering parts (herbs) of Hyssopus officinalis subsp. aristatus (Godr.) Nyman (Lamiaceae) collected from five different locations in Montenegro, or purchased in Serbia, were investigated. In addition, their antibacterial activity in combination with antibiotics was s...
By Tijana Mićović, Dušan Ušjak, Marina Milenković, Stevan Samardžić, Zoran Maksimović
Alternaria leaf spot on Paeonia peregrina and Paeonia tenuifolia in Serbia
Paeonia peregrina Mill. and Paeonia tenuifolia L. are endangered species of herbaceous plants with high ornamental and medicinal values. There are a few natural habitats in Serbia where these plants spontaneously grow: Krivi Vir, Skrobnica, Golina, Pirot, Deliblato Sands, and Sokobanja, in the municipality of Knjaževac. In July 2021, the symp...
By Sara Mikić, Tatjana Marković, Nina Vučković, Željana Prijić, Jingqi Xue