Assessment of antioxidant and hepatoprotective potential of Satureja montana extracts against CCl4 induced liver damage
The influence of Satureja montana extracts on several liver biochemical parameters in mice administered with carbon tetrachloride was estimated. In vivo investigation of antioxidant properties of S. montana extracts encompassed monitoring of biochemical parameters (derived from liver homogenate and blood hydrolyzate) and examination of potential he...
By Tatjana Ćebović, Jelena Vladić, Aleksandra Gavarić, Zoran Zekanović, Senka Vidović
Variation of parthenolide and phenolic compounds content in different parts of Tanacetum parthenium (L.) Schulz Bip., Asteraceae during 18 months storage
Tanacetum parthenium (L.) Schulz Bip., Asteraceae (feverfew), being a medicinal plant with a long tradition in European folk medicine, has been used to treat headache, fever, rheumatism, asthma, stomach pains, and other conditions related to inflammation. Although feverfew is often used for migraine headaches, numerous literature data stated the in...
By Vladan Tadić, Jelena Živković, Dubravka Bigović, Ana Žugić
Investigation of stability of cold pressed linseed (Linum usitatissimum L.) oil
The stability of linseed (Linum usitatissimum) oil has been investigated through the exposition of two different samples, linseed oil without antioxidant and linseed oil with roesemary (Rosmarinus officinalis) extract, to ambient temperature conditions (25 °C) and refrigerator temperature conditions (4 °C). The oxidation degree of linseed oi...
By Zorica Drinić, Jelena Mudrić, Gordana Zdunić, Dubravka Bigović, Katarina Šavikin
Novel insights to the anti-proliferative activity of rosemary (Rosmarinus officinalis L.) co-treatment
The aim of this study was to characterize volatile and non-volatile compounds of rosemary from the North Adriatic region and to determine its antiproliferative activity, alone or in combination with radiomimetic bleomycin (BLM) on three malignant and one non-transformed human cell line. Chemical analysis of the volatile compounds revealed the prese...
By Jasminka Mrđanović, Višnja Bogdanović, Biljana Kiprovski, Đorđe Malenčić, Maja Mikulič-Petkovšek, Ivan Milovanović, Aleksandra Mišan
Diploid vs. tetraploid Centaurium erythraea Rafn: a comparative study of regenerative in vitro potential and biosynthetic capacity
The impact of ploidy level on both the regenerative potential under in vitro conditions and the production of major bioactive specialized metabolites, such are iridoids and xanthones, was examined in Centaurium erythraea Rafn. Shoot regeneration frequency was genotype dependent, but not affected by explant ploidy level. In most cases, the regenerat...
By Biljana Filipović, Branislav Šiler, Jasmina Nestorović-Živković, Tijana Banjanac, Marijana Skorić, Jelena Božunović, Danijela Mišić
In vitro evaluation of antioxidant, antineurodegenerative and antidiabetic activities of Ocimum basilicum L., Laurus nobilis L. leaves and Citrus reticulata Blanco peel extracts
<i>Ocimum basilicum<i> (sweet basil) and <i>Laurus nobilis</i> (bay leaves or laurel) have been used in traditional medicine for centuries, and also extensively employed as spices for adding aroma and flavor to various food products. <i>Citrus reticulata</i> (mandarin) is mainly used in food industry for ju...
By Sonja Duletić-Laušević, Mariana Oalđe, Ana Alimpić-Aradski
Exploring the attitude of Faculty of Medicine students about herbal products usage: a cross-sectional study
Herbal products have gained popularity, and they are often perceived as safe. The roles of the pharmacists and physicians are essential in the proper usage of those products. This study aimed to investigate the students of Faculty of Medicine in Niš about the use of herbal preparations and the differences between medicine, pharmacy and denti...
By Emilija Kostić, Milica MIlutinović, Milica Kostić, Jasmina Petrović, Bojana Miladinović, Suzana Branković, Maja Vujović, Dušanka Kitić
Double emulsions (W/O/W emulsions): Encapsulation of Plant Biactives
This article describes the preparation, characterization, and application of W/O/W emulsions, with emphasis on the encapsulation of plant bioactives. The main limitations preventing commercialization of double emulsions with plant bioactive substances, used for the preparation of food, nutraceuticals and pharmaceuticals for oral administration, are...
By Jelena Mudrić, Katarina Šavikin, Svetlana Ibrić, Jelena Đuriš
The influence of the extraction method on the content of silymarin in Silybi mariani fructus
This study was aimed to compare the efficiency of silymarin extraction from Silybi mariani fructus using different extraction methods. Maceration, percolation, extraction in a water bath, and ultrasonicassisted extraction have been performed with 60% ethanol. Extracts were analyzed using UV/Vis and HPLC techniques. Our results showed that the highe...
By Sofija Đorđević, Teodora Janković, Milica Mihailović
Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method
Due to its high content of phenolics, black chokeberry has been proposed as a health-promoting material, especially use of chokeberry extract as a food or pharmaceuticals. Chokeberry extract was spray-dried using gum Arabic as a carrier. The optimal conditions for the efficient microencapsulation of chokeberry extract using spray-drying technique h...
By Nada Čujić-Nikolić, Nemanja Stanisavljević, Katarina Šavikin, Ana Kalaušević, Viktor Nedović, Dubravka Bigović, Teodora Janković