Cytotoxic activity of supercritical CO2 extract of old man’s beard in L929 fibrosarcoma cell line
Usnea barbata (old man’s beard) is one of the most investigated lichens which biological properties (such as antimicrobial, anti-inflammatory and cytotoxic activities) have been proven in several scientific studies. Stated properties of old man’s beard have been attributed mainly to its major secondary metabolite - a dibenzofuran deriva...
By Ana Žugić, Aleksandra Isaković, Ivica Jeremić, Vanja Tadić
Variation of parthenolide and phenolic compounds content in different parts of Tanacetum parthenium (L.) Schulz Bip., Asteraceae during 18 months storage
Tanacetum parthenium (L.) Schulz Bip., Asteraceae (feverfew), being a medicinal plant with a long tradition in European folk medicine, has been used to treat headache, fever, rheumatism, asthma, stomach pains, and other conditions related to inflammation. Although feverfew is often used for migraine headaches, numerous literature data stated the in...
By Vladan Tadić, Jelena Živković, Dubravka Bigović, Ana Žugić
Investigation of stability of cold pressed linseed (Linum usitatissimum L.) oil
The stability of linseed (Linum usitatissimum) oil has been investigated through the exposition of two different samples, linseed oil without antioxidant and linseed oil with roesemary (Rosmarinus officinalis) extract, to ambient temperature conditions (25 °C) and refrigerator temperature conditions (4 °C). The oxidation degree of linseed oi...
By Zorica Drinić, Jelena Mudrić, Gordana Zdunić, Dubravka Bigović, Katarina Šavikin
Novel insights to the anti-proliferative activity of rosemary (Rosmarinus officinalis L.) co-treatment
The aim of this study was to characterize volatile and non-volatile compounds of rosemary from the North Adriatic region and to determine its antiproliferative activity, alone or in combination with radiomimetic bleomycin (BLM) on three malignant and one non-transformed human cell line. Chemical analysis of the volatile compounds revealed the prese...
By Jasminka Mrđanović, Višnja Bogdanović, Biljana Kiprovski, Đorđe Malenčić, Maja Mikulič-Petkovšek, Ivan Milovanović, Aleksandra Mišan
Diploid vs. tetraploid Centaurium erythraea Rafn: a comparative study of regenerative in vitro potential and biosynthetic capacity
The impact of ploidy level on both the regenerative potential under in vitro conditions and the production of major bioactive specialized metabolites, such are iridoids and xanthones, was examined in Centaurium erythraea Rafn. Shoot regeneration frequency was genotype dependent, but not affected by explant ploidy level. In most cases, the regenerat...
By Biljana Filipović, Branislav Šiler, Jasmina Nestorović-Živković, Tijana Banjanac, Marijana Skorić, Jelena Božunović, Danijela Mišić
In vitro evaluation of antioxidant, antineurodegenerative and antidiabetic activities of Ocimum basilicum L., Laurus nobilis L. leaves and Citrus reticulata Blanco peel extracts
<i>Ocimum basilicum<i> (sweet basil) and <i>Laurus nobilis</i> (bay leaves or laurel) have been used in traditional medicine for centuries, and also extensively employed as spices for adding aroma and flavor to various food products. <i>Citrus reticulata</i> (mandarin) is mainly used in food industry for ju...
By Sonja Duletić-Laušević, Mariana Oalđe, Ana Alimpić-Aradski
Exploring the attitude of Faculty of Medicine students about herbal products usage: a cross-sectional study
Herbal products have gained popularity, and they are often perceived as safe. The roles of the pharmacists and physicians are essential in the proper usage of those products. This study aimed to investigate the students of Faculty of Medicine in Niš about the use of herbal preparations and the differences between medicine, pharmacy and denti...
By Emilija Kostić, Milica MIlutinović, Milica Kostić, Jasmina Petrović, Bojana Miladinović, Suzana Branković, Maja Vujović, Dušanka Kitić
Double emulsions (W/O/W emulsions): Encapsulation of Plant Biactives
This article describes the preparation, characterization, and application of W/O/W emulsions, with emphasis on the encapsulation of plant bioactives. The main limitations preventing commercialization of double emulsions with plant bioactive substances, used for the preparation of food, nutraceuticals and pharmaceuticals for oral administration, are...
By Jelena Mudrić, Katarina Šavikin, Svetlana Ibrić, Jelena Đuriš
Microencapsulation methods for plants biologically active compounds - a review
Biologically active compounds from plants have attracted great interest due to their affordability, effectiveness and low toxicity. Herbal extracts provide an infinite resource of raw materials for pharmaceutical, cosmetic and food industry. Unfortunately, use of the valuable natural compounds can be limited by their low bioavailability, volatiliza...
By Jelena Mudrić, Svetlana Ibrić, Jelena Đuriš
Chemical composition and biological activities of the extracts and secondary metabolites of lichens belonging to the genus Usnea, Parmeliaceae
Lichens represent a promising source of antimicrobial, cytotoxic and antioxidant agents. Their great pharmacological potential lies in the fact that they represent specific symbiotic organisms and thus possess natural roles allowing them to be highly adaptable to different environmental conditions. On the other hand, stated biological activities of...
By Ana Zugić, Vanja Tadić, Tatjana Kundaković, Snežana Savić