High doses of Uvaria chamae root extract impair sperm motility and viability
Uvaria chamae is a tropical medicinal plant with documented antimicrobial and antimalarial activities. Agents with these activities are known to impair fertility. This study investigated the antifertility effects of ethanolic extract of U. chamae on male albino Wistar rats. Two different oral doses; 56.6 mg/kg body weight and 113.2 mg/kg body weigh...
By Godwin Adakole Ujah, Ileri-Oluwa Busayo Emmanuel, Bassey Emmanuel Emeng, Patience Favour Kalu
Hawthorn (Crataegus spp.) from botanical source to phytopreparations
The usage of hawthorn preparations has a long history in the traditional treatment of heart failure, which is considered as the inability of a weakened heart to supply peripheral tissues with the required amount of oxygen and nutrients. The leaf, flower, and fruit of the hawthorn, due to the presence of bioactive compounds such as flavonoids, procy...
By Sofija Đorđević, Nada Čujić-Nikolić
Enzyme inhibitors as controllers of neurodegenerative diseases: An update of in vitro effects of medicinal plants
Considering the increase of the elderly population in recent years, the growing prevalence of age-related neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD) and Parkinson’s disease (PD), has become one of the leading healthcare problems. Currently, available therapies for AD and PD are still limited, while medicinal p...
By Ana Alimpić-Aradski, Mariana Oalđe-Pavlović, Smiljana Janković, Petar D.Marin, Sonja Duletić-Laušević
Comprehensive combined chemical and pharmacognostic approach in the investigation of Montenegrin flora, with emphasis on endemic species: Past performance and future potential
Herein, we have reviewed the comparative analysis relating pharmacognostic and chemical approaches in the investigation of the chosen plants from Montenegrin flora known for the constituents recognized as carriers of different biological activities. In addition, some of the mentioned extensively studied plants were with uncertain status in the syst...
By Nebojša R.Menković, Vanja M.Tadić
Antifungal activity of aqueous and corn steep liquor extract of Ficus exasperata, Anonna muricata and Azadiractha indica
This study investigated the activity of aqueous and corn steep liquor (CSL) extracts of Ficus exaperasta, Azadirachta indica and Annona muricata against Candida spp isolated from high vagina swab samples. Phytochemical screening of the plants was done using standard methods, the antifungal activity of the plant’s extracts and standard drugs w...
By Temilola Akinkunbed, Samuel Bankole, Paul Ogunbamwo, Olamilekan Awotedu
Cultivation cost-benefit analysis of some important medicinal plants in Serbia
Driven by frequent media misinformation about the level of profitability of growing certain medicinal plants, in this paper we presented a cost-benefit analysis based on twenty years of experience in field production. The observed costs and profits for peppermint, chamomile, lemon balm, marshmallow, valerian and pot marigold are based on the averag...
By Dejan Pljevljakušić, Sreta Brkić
Extraction of sweet wormwood (Artemisia annua L.) by supercritical carbon dioxide
In this study, supercritical carbon dioxide was applied for the extraction of Artemisia annua L. Moreover, the impact of different parameters of supercritical extraction on total yield was investigated and the obtained yields were compared to the ones obtained by conventional procedures, hydrodistillation and Soxhlet extraction. Supercritical fluid...
By Senka Vidović, Siniša Simić, Aleksandra Gavarić, MIlica Aćimović, Jelena Vladić
Ethnomedicinal application of species from genus Thymus in the Pirot County (Southeastern Serbia)
The species from genus Thymus are polymorphous plants from the family Lamiaceae, spread in Serbia in many species, subspecies, varieties, and forms. The aerial parts of species from genus Thymus have a long tradition of being used worldwide. The subject of this study was the research of ethnomedicinal application of thyme in Pirot County (Southeast...
By Marija Marković, Dejan Pljevljakušić, Biljana Nikolić, Ljubinko Rakonjac, Vesna Stankov-Jovanović
GC/MS chemical analysis of lavandin (Lavandula x intermedia) hydrolat: successive extraction fractions
Hydrolats are valuable co-products of the essential oil distillation process, whose volatile compounds can be quantified by various methods. In this paper, we have tried to estimate the liquid-liquid extraction cycle number threshold for volatile compounds quantification of lavandin (Lavandula x intermedia) hydrolat. For this purpose, ten consecuti...
By Dejan Pljevljakušić, Zorica Drinić
Development of gastroretentive floating granules with gentian root extract by hot-melt granulation
The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of the solid pharmaceutical forms. Gentiopicroside, as a dominant secoiridoid in the GRE, has a sho...
By Jelena Mudrić, Mirjana Pajić, Dubravka Bigović, Jelena Đuriš