The following study was designed to explore antimicrobial properties of the by-product obtained in a hydro-distillation process of essential oil from Nepeta nuda L. We strived to develop a novel drink with antimicrobial self-preserving properties based on two components, N. nuda decoct and apple juice. By using 96-well plate microdilution assay it ...

By Uroš Gašić, Dejan Stojković, Marija Ivanov, MIlica Miletić, Danijela Mišić, Milan Veljić, Marina Soković

Telekia speciosa (Schreb.) Baumg., Asteraceae, is widespread in Eastern and Central Europe and the Balkan Peninsula. Previous phytochemical investigations have revealed T. speciosa as a rich source of sesquiterpene lactone – isoalantolactone, especially in its underground parts. The aim of the present study was to analyze the essential oils f...

By Ermina Cilović-Kozarević, Broza Šarić-Kundalić, Merima Ibišević, Emir Horozić, Jasmina Glamočlija, Marina Soković, Jelena Arsenijević, Zoran Maksimović

Willowherb (Epilobium angustifolium L.) leaves are a valuable source of polyphenolic compounds (phenolic acids, flavonoids, and ellagitannins) that are mainly used in the treatment of benign prostatic hyperplasia. In the presented study, the impacts of maltodextrin and whey protein as carriers on the efficiency of spray drying and physicochemical p...

By Miloš Janković, Zorica Drinić, Dubravka Bigović, Gordana Zdunić, Jelena Mudrić, Katarina Šavikin

The paper provides an insight into the traditional use of medicinal plant species from the genus Gentiana in the Pirot County in Southeastern Serbia. The ethnopharmacological study was conducted in the form of interviews among the population in four municipalities: Pirot, Babušnica, Bela Palanka, and Dimitrovgrad. Among the population of Pir...

By Marija Marković, Dejan Pljevljakušić, Nebojša Menković, Jelena Matejić, Olivera Papović, Vesna Stankov-Jovanović

The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of the solid pharmaceutical forms. Gentiopicroside, as a dominant secoiridoid in the GRE, has a sho...

By Jelena Mudrić, Mirjana Pajić, Dubravka Bigović, Jelena Đuriš

This study aimed to assess the antineurodegenerative and antioxidant activity of Helichrysum plicatum flower extract, as well as to identify extract ingredients with acceptable pharmacokinetic parameters such as gastrointestinal absorption, blood-brain barrier permeation, and P-glycoprotein-mediated effusion for optimal therapeutic brain exposure. ...

By Miloš Jovanović, Zorica Drinić, Dubravka Bigović, Ana Alimpić-Aradski, Sonja Duletić-Laušević, Katarina Šavikin

Fruticin (amorphin) is a constituent of the fruit of the false indigo-bush (Amorpha fruticosa L.), which belongs to the class of rotenoid glycosides, and shows several interesting pharmacological activities. The aim of this study was to isolate and chemically characterize this natural product, as well as to determine the optimal period of the year ...

By Stevan Samardžić, Aleksandra Tucović, Danilo Stojanović, Zoran Maksimović

Staphylococcus aureus is a human pathogen that causes serious infections with high mortality rates. The antimicrobial activities of eight phenolic compounds (caffeic acid, chlorogenic acid, ferulic acid, morin, quercetin, isoquercitrin, rutin and hesperidin) were evaluated against planktonic and biofilm forming Staphylococcus aureus cells. Their ab...

By Marina Kostić, Marija Ivanov, Dejan Stojković, Ana Ćirić, Marina Soković

This study represents a continuation of exploring of the biological activities of the Artemisia santonicum essential oil. The previous investigation was focused on the antibacterial, antibiofilm, and antiquorum activities of A. santonicum essential oil and isogeranic acid as the main antibacterial constituent. The present study describes their anti...

By Jovana Stankov-Jovanović, Miroslav Novaković, Miroslav Novaković, Vele Tešević, Gordana Zdunić, Zora Dajić Stevanović, Dejan Gođevac

Lady’s mantle (Alchemilla vulgaris L. syn. Alchemilla xanthochlora Rothm., Rosaceae) has been commonly used in folk medicine to heal inflammations in the mouth, bleeding of the nose, furuncules, gynaecological (menorrhagia and dysmenorrhoea), and gastrointestinal disorders. Although therapeutic indications for Lady’s mantle are non-specific diarrho...

By Vanja Tadić, Nemanja Krgović, Ana Žugić