Evaluation of antioxidant activities and haematological effects of Asystasia gangetica leaf extract in monosodium glutamate-treated rats
This study evaluated antioxidant activities and haematological effects of methanol extract of Asystasia gangetica leaves (MEAG) on monosodium glutamate (MSG) treated rats. Forty-two male Wistar rats randomly distributed into 7 groups (n=6) were used for the study. Groups 1-3 were the normal control, MSG control, and positive control respectively wh...
By Robert Uroko, Amarachi Agbafor, Simeon Egba, Chinedu Nwuke, Sharon Kalu-Kalu
Qualitative and quantitative phytochemical evaluation of Quassia undulata (Guill. & Perr.) D. Dietr. leaves using different solvent polarities
This study investigated solvent effects on the phytochemical composition of Quassia undulata leaves a medicinal plant used in treating arrays of diseases including fever and cough. The leaves were collected, washed, air-dried, pulverized and evaluated for some inherent phytochemicals using four different solvent systems based on their polarities. T...
By Ibraheem Oduola-Lawal, Adeniyi Olufunso, Ariwoola Oluwole
Evaluation of different solvents for phytochemical constituents and antioxidant activities of the leaves of Acanthus montanus (Nees) T. Anderson
Bear’s breech or mountain thistle (Acanthus montanus (Nees) T. Anderson) is a shrub belonging to Acanthaceae family. It is widespread in Africa, Romania, Greece, and Eastern Mediterranean. African people engage its medicinal use for the management of urethral pain, endometritis, urogenital infections, urinary disease, aches and pains. Fresh l...
By Ale Joy Enitan, Lawal Ibraheem Oduola, Omogbene Temitope Olorunyomi
Microwave-assisted extraction of essential oil from ginger (Zingiber officinale Rosc.)
Comparison between conventional and microwave-assisted hydrodistillation at different power levels has been applied for the extraction of essential oil from Zingiber officinale Rosc. rhizome. In addition to the collected essential oils, as the main products, hydrolats were also collected, as valuable by-products from both extraction techniques. A c...
By Zorica Drinić, Miloš Jovanović, Dejan Pljevljakušić, Nada Čujić-Nikolić, Dubravka Bigović, Katarina Šavikin
Cultivation cost-benefit analysis of some important medicinal plants in Serbia
Driven by frequent media misinformation about the level of profitability of growing certain medicinal plants, in this paper we presented a cost-benefit analysis based on twenty years of experience in field production. The observed costs and profits for peppermint, chamomile, lemon balm, marshmallow, valerian and pot marigold are based on the averag...
By Dejan Pljevljakušić, Sreta Brkić
Extraction of sweet wormwood (Artemisia annua L.) by supercritical carbon dioxide
In this study, supercritical carbon dioxide was applied for the extraction of Artemisia annua L. Moreover, the impact of different parameters of supercritical extraction on total yield was investigated and the obtained yields were compared to the ones obtained by conventional procedures, hydrodistillation and Soxhlet extraction. Supercritical fluid...
By Senka Vidović, Siniša Simić, Aleksandra Gavarić, MIlica Aćimović, Jelena Vladić
Ethnomedicinal application of species from genus Thymus in the Pirot County (Southeastern Serbia)
The species from genus Thymus are polymorphous plants from the family Lamiaceae, spread in Serbia in many species, subspecies, varieties, and forms. The aerial parts of species from genus Thymus have a long tradition of being used worldwide. The subject of this study was the research of ethnomedicinal application of thyme in Pirot County (Southeast...
By Marija Marković, Dejan Pljevljakušić, Biljana Nikolić, Ljubinko Rakonjac, Vesna Stankov-Jovanović
GC/MS chemical analysis of lavandin (Lavandula x intermedia) hydrolat: successive extraction fractions
Hydrolats are valuable co-products of the essential oil distillation process, whose volatile compounds can be quantified by various methods. In this paper, we have tried to estimate the liquid-liquid extraction cycle number threshold for volatile compounds quantification of lavandin (Lavandula x intermedia) hydrolat. For this purpose, ten consecuti...
By Dejan Pljevljakušić, Zorica Drinić
Development of gastroretentive floating granules with gentian root extract by hot-melt granulation
The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of the solid pharmaceutical forms. Gentiopicroside, as a dominant secoiridoid in the GRE, has a sho...
By Jelena Mudrić, Mirjana Pajić, Dubravka Bigović, Jelena Đuriš
In vitro and in silico prediction of antineurodegenerative properties of Helichrysum plicatum flower extract
This study aimed to assess the antineurodegenerative and antioxidant activity of Helichrysum plicatum flower extract, as well as to identify extract ingredients with acceptable pharmacokinetic parameters such as gastrointestinal absorption, blood-brain barrier permeation, and P-glycoprotein-mediated effusion for optimal therapeutic brain exposure. ...
By Miloš Jovanović, Zorica Drinić, Dubravka Bigović, Ana Alimpić-Aradski, Sonja Duletić-Laušević, Katarina Šavikin