Bear’s breech or mountain thistle (Acanthus montanus (Nees) T. Anderson) is a shrub belonging to Acanthaceae family. It is widespread in Africa, Romania, Greece, and Eastern Mediterranean. African people engage its medicinal use for the management of urethral pain, endometritis, urogenital infections, urinary disease, aches and pains. Fresh l...

By Ale Joy Enitan, Lawal Ibraheem Oduola, Omogbene Temitope Olorunyomi

Comparison between conventional and microwave-assisted hydrodistillation at different power levels has been applied for the extraction of essential oil from Zingiber officinale Rosc. rhizome. In addition to the collected essential oils, as the main products, hydrolats were also collected, as valuable by-products from both extraction techniques. A c...

By Zorica Drinić, Miloš Jovanović, Dejan Pljevljakušić, Nada Čujić-Nikolić, Dubravka Bigović, Katarina Šavikin

The following study was designed to explore antimicrobial properties of the by-product obtained in a hydro-distillation process of essential oil from Nepeta nuda L. We strived to develop a novel drink with antimicrobial self-preserving properties based on two components, N. nuda decoct and apple juice. By using 96-well plate microdilution assay it ...

By Uroš Gašić, Dejan Stojković, Marija Ivanov, MIlica Miletić, Danijela Mišić, Milan Veljić, Marina Soković

Telekia speciosa (Schreb.) Baumg., Asteraceae, is widespread in Eastern and Central Europe and the Balkan Peninsula. Previous phytochemical investigations have revealed T. speciosa as a rich source of sesquiterpene lactone – isoalantolactone, especially in its underground parts. The aim of the present study was to analyze the essential oils f...

By Ermina Cilović-Kozarević, Broza Šarić-Kundalić, Merima Ibišević, Emir Horozić, Jasmina Glamočlija, Marina Soković, Jelena Arsenijević, Zoran Maksimović

The species from genus Thymus are polymorphous plants from the family Lamiaceae, spread in Serbia in many species, subspecies, varieties, and forms. The aerial parts of species from genus Thymus have a long tradition of being used worldwide. The subject of this study was the research of ethnomedicinal application of thyme in Pirot County (Southeast...

By Marija Marković, Dejan Pljevljakušić, Biljana Nikolić, Ljubinko Rakonjac, Vesna Stankov-Jovanović

Hydrolats are valuable co-products of the essential oil distillation process, whose volatile compounds can be quantified by various methods. In this paper, we have tried to estimate the liquid-liquid extraction cycle number threshold for volatile compounds quantification of lavandin (Lavandula x intermedia) hydrolat. For this purpose, ten consecuti...

By Dejan Pljevljakušić, Zorica Drinić

The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of the solid pharmaceutical forms. Gentiopicroside, as a dominant secoiridoid in the GRE, has a sho...

By Jelena Mudrić, Mirjana Pajić, Dubravka Bigović, Jelena Đuriš

This study aimed to assess the antineurodegenerative and antioxidant activity of Helichrysum plicatum flower extract, as well as to identify extract ingredients with acceptable pharmacokinetic parameters such as gastrointestinal absorption, blood-brain barrier permeation, and P-glycoprotein-mediated effusion for optimal therapeutic brain exposure. ...

By Miloš Jovanović, Zorica Drinić, Dubravka Bigović, Ana Alimpić-Aradski, Sonja Duletić-Laušević, Katarina Šavikin

Fruticin (amorphin) is a constituent of the fruit of the false indigo-bush (Amorpha fruticosa L.), which belongs to the class of rotenoid glycosides, and shows several interesting pharmacological activities. The aim of this study was to isolate and chemically characterize this natural product, as well as to determine the optimal period of the year ...

By Stevan Samardžić, Aleksandra Tucović, Danilo Stojanović, Zoran Maksimović

Staphylococcus aureus is a human pathogen that causes serious infections with high mortality rates. The antimicrobial activities of eight phenolic compounds (caffeic acid, chlorogenic acid, ferulic acid, morin, quercetin, isoquercitrin, rutin and hesperidin) were evaluated against planktonic and biofilm forming Staphylococcus aureus cells. Their ab...

By Marina Kostić, Marija Ivanov, Dejan Stojković, Ana Ćirić, Marina Soković