PHARAMACEUTICAL HYALURONIC ACID BASED CARRIERS FOR PARENTERAL USE, PARTICULARLY CONJUGATES WITH TAXOL: A REVIEW
In recent years, drug delivery systems are especially interesting because they allow therapeutic efficiency and reduce side effects. Conjugates of hyaluronic acid and chemotherapeutic agents, especially taxol, have been recognized as excellent solution for many therapeutic indications. The aim of conjugation of taxol with hyaluronic acid was the to...
By Nada Ćujić, Svetlana Ibrić, Dubravka Bigović, Nebojša Noveski, Katarina Šavikin
IN VITRO ANTITUMORAL ACTIVITY OF THE EXTRACT OF SPONGE ACANTHELLA ACUTA
Seaweeds are an excellent source of compounds with biological activity.Particularly interesting are the sponges, which suited in medicine reaches into the distant past. The biological effects of extracts and new compounds from sponges have been reported in numbers of scientific papers. Sponges produce a plethora of chemical compounds with widely va...
By Tatjana Stanojković, Sanja Milović, Ivana Matić, Nađa Grozdanić, Zoran Kljajić
A REWIEW OF PHARMACOLOGICAL PROPERTIES OF ANISE (PIMPINELLA ANISUM L.)
Anise (Pimpinella anisum L.) is an annual plant that belongs to the Apiaceae family. It is grown for fruit (Anisi fructus), containing 2-3% essential oil (Anisi aethroleum) with trans-anethole which is a dominant compound and has a characteristic sweet taste and smell. Anise is used in folk medicine in many countries for treatment of digestive, res...
By Milica Aćimović, Nevena Dojčinović
HERBS AND NATURAL PRODUCTS IN PREVENTION AND TREATMENT OF MIGRAINE
Migraine headaches are extremely common and it is considered that, on average, one of ten people suffer from migraine. The pathogenesis of migraine is not fully understood. There are two theories, vascular and neurogenic. The treatment of migraine involves the prevention and treatment of acute attacks. Preventive therapy is recommended when migrain...
By Milan Ilić
EXPERIMENTAL METHODS APPLICABLE IN CULTIVATION OF MEDICINAL PLANTS
This work summarizes the most commonly used methods of research of weed species in medicinal herbs. The choice of method depends on the type of research that we want to conduct. The methods relating to weed herbs are described in detail for the methods of examination of the weeds’ seed germination, methods for the determination of reserves of...
By Ana Matković, Sava Vrbničanin, Tatjana Marković, Dragana Božić
MEDICINAL POTENTIAL OF CUCURBITA POLYSACCHARIDES
Pumpkin has been used frequently as functional food or medicine. In recent years due to numerous pharmacological effects, pumpkin polysaccahrides attract increased attention from researchers. Different investigations showed their antidiabetic, antioxidant, hypolipidemic, antibacterial and antitussive effect. Since most of the studies with pumpkin p...
By Jelena Živković, Katarina Šavikin, Gordana Zdunić, Teodora Janković
IN VITRO PRODUCTION OF CHLOROGENIC ACID IN CULTURE OF TRANSFORMED CICHORIUM INTYBUS L. PLANTS
Chicory (Cichorium intybus L.) is traditionally recognized for its anti-inflammatory, antimicrobial, anticancer and nutritive properties. Among active secondary metabolites detected in chicory, the most important are sesquiterpene lactones and phenolics, including chlorogenic acid (CA). Hereby we have analyzed the content of CA in previously obtain...
By Milica Bogdanović, Milan Dragićević, Angelina Subotić, Ana Simonović, Slađana Todorović
EXTRACTION OF HERBAL DRUGS: COMPRATIVE EXTRACTION OF CIRCULAR AND EXTRACTION WITH SUPERCRITICAL CARBON DIOXIDE
The most commonly used methods of isolation and concentration of certain constituents from herbal drugs with selected solvents are maceration, doubled maceration, digestion, turboextraction, percolation, repercolation, ultrasonic-assisted extraction and counter-current extraction. According to their consistency, extracts can be classified as liquid...
By Ljiljana Savić
AYURVEDA, ITS MAIN MODALITIES AND PRINCIPLES OF VEDIC AROMATHERAPY
According to the World Health Organization, Ayurveda is the oldest medical system in the world that is practiced continuously. It is considered the most complete knowledge and science of healthy living. According to the Vedic scriptures, until the end of the Middle Age, essential oils have been used for religious, medicinal and cosmetic purposes. T...
By Branko Čičić
OBRAZOVANjE, NAUKA I PROIZVODNjA HRANE
U prethodnoj godini, u izdanju Akademije nauka i umjetnosti Republike Srpske izašla je iz štampe monografija „Obrazovanje, nauka i proizvodnja hrane“,autora akademika Vaskrsija Janjića. Radi se o izuzetno vrijednom dijelu u koje je autor uložio ogroman rad i znanje pa je tako stvorio djelo neobično, kompleksno i sadržajno ...
By Branko Škundurić