Veronica officinalis is plant species used in traditional medicine worldwide, but its effects have not been investigated so far. Consequently, the aim of this research was to identify dominant compound in V. officinalis extracts and to determine the effect of ultrasound and extraction temperature on the content of that compound and total phenolic content. Moreover we investigated the correlation between the concentration of dominant compound and antiradical activity of tested extracts. The main compound in extracts was acteoside. Higher amount of total phenolics and acteoside were obtained using ultrasound-assisted extraction technique and higher temperatures. DPPH assay, which is used for measuring antiradical potential, showed that concentration of acteoside, as well as concentration of polyphenolic compounds, is directly correlated with antioxidative potentiality tested extracts.
Ahn, D., Lee, S. I., Yang, J. H., H., C., Cho, Y. H. H., Park, J. H., & Kim, D. K. (2011). Superoxide radical scavengers from the whole plant of Veronica peregrina. Natural Product, Scinces,17, 142–146.
Anesini, C., Ferrara, G. E., & Filip, R. (2008). Total Polyphenol Content and antioxidant capacity of commercialy available tea (Camellia sinensis) in Argentina. Journal of Agricultural and Food Chemistry, 56, 9225–9229.
Chen, C. H., Lin, Y. S., Chien, M. Y., Hou, W. C., & Hu, M. L. (2012). Antioxidant and antihypertensive activities of acteoside and its analogs. Botanical Studies, 53, 421–429.
Crişan, G., Tămas, M., Miclâuş, V., Krusz, T., & Sandor, V. (2007). A comparative study of some Veronica species. Revista Medico-Chiruricala A Societatii de Medici Si Naturalisti Din, Iasi,111, 280–284.
Cuendet, M., Hostettmann, K., Potterat, O., & Dyatmiko, W. (1997). Iridoid glucosides with free radical scavenging properties from Fagraea blumei. Helvetica Chimica, Acta,80, 1144–1152.
Ertas, A., Boga, M., Kizil, M., Ceken, B., Goreu, A. C., Hasimi, N., Demirci, S., Topcu, G., & Kolak, U. (2015). Chemical profile and biological activites of Veronica thymoides subsp. pseudocinerea. Pharmaceutical, Biology,53, 334–339.
Jensen, S. R., Gotfredsen, C. H., Harput, U. S., & Saracoglu, I. (2010). Chlorinated iridoid glucosides from Veronica longifolia and their antioxidant activity. Journal of Natural Products, 73, 1593–1596.
Kothari, V., Gupta, A., & Naraniwal, M. (2012). Comparative study of various methods for extraction of antioxidant and antibacterial compounds from plant seeds. Journal of Natural, Remedies,2, 162–173.
Ljubisavljević, S. (2014). Protektivno dejstvo modulatora oksidativnog i nitrozativnog stresa u neuroinflamaciji – eksperimentalna i klinička studija. In Doktorska disertacija. Univerzitet u Nišu, Medicinski fakultet.
Montvale, N. Y. (n.d.). PDR for herbal medicines (2004): Thomson PDR. Montvale, New Yersey. Uzorak* Sample* Ukupni Fenoli Total Phenolic Content (Mg GAE/Sm) Sadržaj Akteozida Acteoside Content (Mg/g Sm) IC50 (Μg/ML) 1 16,28±1,35 6,24±0,57 155,52±8,23 2 18,57±1,68 7,36±0,44 146,71±6,12 3 18,77±2,11 8,17±0,62 112,83±7,16 4 24,30±2,91 8,51±0,81 106,42±6,83 118, 118.
Velioglu, Y. S., Mazza, G., Gao, L., & Oomah, B. D. (1998). Antioxidant activity and total phenolics in selected fruits, vegetables and grain products. Journal of Agriculture and Food Chemistry, 46, 4113–4117.
Yin, L., Wei, L., Fu, R., Ding, L., Guo, Y., Tang, L., & Chen, F. (2014). Antioxidant and hepatoprotective activity of Veronica ciliata Fisch. extracts against carbon tetrachloride-induced liver injury in mice. Molecules, 19, 7223–7236.
Zdravković, A., Lj. Stanojević, M. S., Cakić, M., Nikolić, V., & Lj. Nikolić, D. I. (2012). Uticaj operativnih uslova i tehnika ekstrakcije na prinos, kinetiku i sastav vodenoetanolnih ekstrakata iz lista koprive (Urtica dioica L. Savremene Tehnologije, 1, 30–37.
Živković, J. (2014). Morfološka, hemijska i farmakološka karakterizacija odabranih vrsta roda Veronica L. Univerzitet u Beogradu, Farmaceutski Fakultet.
Živković, J., Ćebović, T., & Maksimović, Z. (2012). In vivo and in vitro antioxidant effects of three Veronica species. Central European Journal Of, Biology,7, 559–568.
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