In recent years, drug delivery systems are especially interesting because they allow therapeutic efficiency and reduce side effects. Conjugates of hyaluronic acid and chemotherapeutic agents, especially taxol, have been recognized as excellent solution for many therapeutic indications. The aim of conjugation of taxol with hyaluronic acid was the to...

By Nada Ćujić, Svetlana Ibrić, Dubravka Bigović, Nebojša Noveski, Katarina Šavikin

Seaweeds are an excellent source of compounds with biological activity.Particularly interesting are the sponges, which suited in medicine reaches into the distant past. The biological effects of extracts and new compounds from sponges have been reported in numbers of scientific papers. Sponges produce a plethora of chemical compounds with widely va...

By Tatjana Stanojković, Sanja Milović, Ivana Matić, Nađa Grozdanić, Zoran Kljajić

The goal of this work was to introduce the parameter for the precise evaluation of in vitroanti-tumor activity of Plantago altissima, P. lanceolata, P. reniformis, Allium flavum, A. cepa, Tuber aestivum i T. magnatumextracts.For the evaluation of the cell growth human tumor cell lines HeLa, MCF7 and HT-29 were used, as well as cell line derived fro...

By Dragana Četojević-Simin, Ivana Beara, Nataša Simin

Veronica officinalis is plant species used in traditional medicine worldwide, but its effects have not been investigated so far. Consequently, the aim of this research was to identify dominant compound in V. officinalis extracts and to determine the effect of ultrasound and extraction temperature on the content of that compound and total phenolic c...

By Biljana Anđelković, Jelena Živković, Katarina Šavikin

Fennel (Foeniculum vulgare Mill.) is aromatic plant from Apiaceae family. There are two types that have commercial importance, sweet fennel Foeniculum vulgare var. dulce, and bitter fennel – Foeniculum vulgare var. vulgare. The aim of this study was to examine the quality of essential oil of the fruits of these two varieties. Plants were grow...

By Milica Aćimović, Nataša Milić

This paper examines the influence of agro-ecological conditions and plantation periods on the occurrence of planting dates of flower stalks, offering fresh and dried valerian root. The aim of this paper is to solve one of the technological unknowns in primary production of valerian roots, where one group of manufacturers base their production on fa...

By Vladimir Filipović, Milica Aćimović, Vladan Ugrenović, Dragoja Radanović, Tatjana Marković, Vera Popović, Ana Matković

The present study was aimed to investigate antioxidant and antimicrobial potential of methanol and ethyl-acetate extracts from dried aerial parts, inflorescences and fruits of Opopanax hispidus (Friv.) Griseb., fam. Apiaceae. The antioxidant potential was evaluated with the help of two in vitro antioxidant models – DPPH and ABTS assays and es...

By Jelena Matejić, Ana Džamić, Tatjana Mihajilov-Krstev, Vladimir Ranđelović, Petar Marin

The aim of this study was to investigate the chemical composition and antifungal activity of four essential oils from Apiaceae family, Pastinaca sativa, Foeniculum vulgare, Pimpinella anisum and Anethum graveolens, against Candida spp. reference strains and clinical isolates from human oral cavities. Chemical analysis of the essential oils (GCFID a...

By Miloš Nikolić, Tatjana Marković, Ana Ćirić, Jasmina Glamočlija, Dejan Marković, Marina Soković

Plant diseases caused by infection with pathogenic fungi can lead to the reduction in the capacity of plant growth or can cause far more serious damage, leading to the death of plants and significant losses in food production. Numerous recent studies are devoted to the investigation of bacteria from genus Bacillus as producers of secondary metaboli...

By Ivica Dikić, Tatjana Stević, Tanja Berić, Ivan Nikolić, Tamara Janakiev, Đorđe Fira, Slaviša Stanković

The aim of this study was to show the results of the perennial fennel (Foeniculum vulgare Mil) production in an isolation zone of organic production. Since this plant species is being used in the pharmaceutical and food industry, its production in an organic farming system has special significance. Isolation zone was founded on an organic demo fiel...

By Vladan Ugrenović, Vladimir Filipović, Stojan Jevremović, Milan Ugrinović