HERBAL DRUGS OF THE LOCAL ORIGIN WITH ANALGESIC ACTIVITY
Pain is a conscious, unpleasant sensory and emotional experience associated with the existing (current) tissue damage. In general, pain is whatever the patient says it hurts. In the literature we can find many definitions of pain, but in life this is really the most uncomfortable feeling that occurs in the body, and therefore is not surprising that...
By Jovana Kvržić
PHARAMACEUTICAL HYALURONIC ACID BASED CARRIERS FOR PARENTERAL USE, PARTICULARLY CONJUGATES WITH TAXOL: A REVIEW
In recent years, drug delivery systems are especially interesting because they allow therapeutic efficiency and reduce side effects. Conjugates of hyaluronic acid and chemotherapeutic agents, especially taxol, have been recognized as excellent solution for many therapeutic indications. The aim of conjugation of taxol with hyaluronic acid was the to...
By Nada Ćujić, Svetlana Ibrić, Dubravka Bigović, Nebojša Noveski, Katarina Šavikin
IN VITRO ANTITUMORAL ACTIVITY OF THE EXTRACT OF SPONGE ACANTHELLA ACUTA
Seaweeds are an excellent source of compounds with biological activity.Particularly interesting are the sponges, which suited in medicine reaches into the distant past. The biological effects of extracts and new compounds from sponges have been reported in numbers of scientific papers. Sponges produce a plethora of chemical compounds with widely va...
By Tatjana Stanojković, Sanja Milović, Ivana Matić, Nađa Grozdanić, Zoran Kljajić
NON-TUMOR/TUMOR IC50 RATIO AS PARAMETER FOR EVALUATION OF IN VITRO ANTITUMOR ACTIVITY OF THE PLANTAGO, ALLIUM AND TUBER SPECIES
The goal of this work was to introduce the parameter for the precise evaluation of in vitroanti-tumor activity of Plantago altissima, P. lanceolata, P. reniformis, Allium flavum, A. cepa, Tuber aestivum i T. magnatumextracts.For the evaluation of the cell growth human tumor cell lines HeLa, MCF7 and HT-29 were used, as well as cell line derived fro...
By Dragana Četojević-Simin, Ivana Beara, Nataša Simin
IMPACT OF EXTRACTION PROCEDURE ON CHEMICAL PROFILE AND ANTIOXIDANT EFFECT OF VERONICA OFFICINALIS EXTRACT
Veronica officinalis is plant species used in traditional medicine worldwide, but its effects have not been investigated so far. Consequently, the aim of this research was to identify dominant compound in V. officinalis extracts and to determine the effect of ultrasound and extraction temperature on the content of that compound and total phenolic c...
By Biljana Anđelković, Jelena Živković, Katarina Šavikin
ESSENTIAL OIL COMPOSITION FROM SWEET AND BITTER FENNEL FRUITS FROM SERBIA
Fennel (Foeniculum vulgare Mill.) is aromatic plant from Apiaceae family. There are two types that have commercial importance, sweet fennel Foeniculum vulgare var. dulce, and bitter fennel – Foeniculum vulgare var. vulgare. The aim of this study was to examine the quality of essential oil of the fruits of these two varieties. Plants were grow...
By Milica Aćimović, Nataša Milić
VALERIAN ROOTS (VALERIANA OFFICINALIS L.) PRODUCED IN AUTUMN AND SPRING PLANTING DATE
This paper examines the influence of agro-ecological conditions and plantation periods on the occurrence of planting dates of flower stalks, offering fresh and dried valerian root. The aim of this paper is to solve one of the technological unknowns in primary production of valerian roots, where one group of manufacturers base their production on fa...
By Vladimir Filipović, Milica Aćimović, Vladan Ugrenović, Dragoja Radanović, Tatjana Marković, Vera Popović, Ana Matković
ANTIOXIDANT AND ANTIMICROBIAL POTENTIAL OF OPOPANAX HISPIDUS(APIACEAE) EXTRACTS
The present study was aimed to investigate antioxidant and antimicrobial potential of methanol and ethyl-acetate extracts from dried aerial parts, inflorescences and fruits of Opopanax hispidus (Friv.) Griseb., fam. Apiaceae. The antioxidant potential was evaluated with the help of two in vitro antioxidant models – DPPH and ABTS assays and es...
By Jelena Matejić, Ana Džamić, Tatjana Mihajilov-Krstev, Vladimir Ranđelović, Petar Marin
SUSCEPTIBILITY OF ORAL CANDIDA SPP. REFERENCE STRAINS AND CLINICAL ISOLATES TO SELECTED ESSENTIAL OILS OF APIACEAE SPECIES
The aim of this study was to investigate the chemical composition and antifungal activity of four essential oils from Apiaceae family, Pastinaca sativa, Foeniculum vulgare, Pimpinella anisum and Anethum graveolens, against Candida spp. reference strains and clinical isolates from human oral cavities. Chemical analysis of the essential oils (GCFID a...
By Miloš Nikolić, Tatjana Marković, Ana Ćirić, Jasmina Glamočlija, Dejan Marković, Marina Soković
IN VITRO ANTIFUNGAL POTENTIAL OF BACILLUS SPP. ISOLATES AS BIOCONTROL AGENTS
Plant diseases caused by infection with pathogenic fungi can lead to the reduction in the capacity of plant growth or can cause far more serious damage, leading to the death of plants and significant losses in food production. Numerous recent studies are devoted to the investigation of bacteria from genus Bacillus as producers of secondary metaboli...
By Ivica Dikić, Tatjana Stević, Tanja Berić, Ivan Nikolić, Tamara Janakiev, Đorđe Fira, Slaviša Stanković