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Pregledni rad – Review Paper

MEDICINAL POTENTIAL OF CUCURBITA POLYSACCHARIDES

By
Jelena Živković ,
Jelena Živković

Institute for Medicinal Plants Research “Dr. Josif Pančić” , Belgrade , Serbia

Katarina Šavikin ,
Katarina Šavikin

Institute for Medicinal Plants Research “Dr. Josif Pančić” , Belgrade , Serbia

Gordana Zdunić ,
Gordana Zdunić

Institute for Medicinal Plants Research “Dr. Josif Pančić” , Belgrade , Serbia

Teodora Janković
Teodora Janković

Institute for Medicinal Plants Research “Dr. Josif Pančić” , Belgrade , Serbia

Abstract

Pumpkin has been used frequently as functional food or medicine. In recent years due to numerous pharmacological effects, pumpkin polysaccahrides attract increased attention from researchers. Different investigations showed their antidiabetic, antioxidant, hypolipidemic, antibacterial and antitussive effect. Since most of the studies with pumpkin polysaccharides have been conducted either in vitro or in animal models, controlled clinical trials are strongly needed to confirm these health-beneficial effects in human subjects. The purpose of the present article is to discuss extraction and characterization of pumpkin polysaccharides as well as their biological potential that can impart further research developments with this plant for human health benefits.


 

References

Du, B., Song, Y., Hu, X., Liao, X., NI, Y., & Li, Q. (2011). Oligosaccharides prepared by acid hydrolysis of polysaccharides from pumpkin (Cucurbita moschata) pulp and their prebiotic activities. International Journal of Food Science and Technology, 46, 982–987.
Durante, M., Lenuci, M. S., & Mita, G. (2014). Supercritical carbon dioxide extraction of carotenoids from pumpkin (Cucurbita spp.): A review. International Journal of Molecular Sciences, 15, 6725–6740.
Fu, C., Shi, H., & Li, Q. (2006). A review on pharmacological activities and utilization technologies of pumpkin. Plant Foods for Human Nutrition, 61, 73–80.
G, G., Adams, S. I., Wang, S., Mohammad, A., Kok, S., Gray, D. A., Channel, G. A., Morris, G. A., & Harding, S. E. (2011). The hypoglycaemic effect of pumpkins as anti-diabetic and functional medicines. 44, 862–867.
Jun, H. I., Lee, C. H., Song, G. S., & Kim, Y. S. (2006). Characterization of the pectic polysaccharides from pumpkin peel. LWT – Food Science and Technology, 35, 554–561.
Koštálová, Z., Hromádková, Z., Ebringerová, A., Polovka, M., Michaelsen, T. E., & Panelsen, B. S. (2013). Polysaccharides from the Styrian oil-pumpkin with antioksidant and complement-fixing activity. Industrial Crops and Products, 41, 127–133.
Matora, A. V., Korshunova, V. E., Shkodina, O. G., Zhemerichkin, D. A., Ptitchkina, N. M., & Morris, E. R. (1995). The application of bacterial enzymes for extraction of pectin from pumpkin and sugar beet. Food Hydrocolloids, 9, 43–46.
Nosálová, G., Prisežnákova, L., Ebringerova, A., Hramádková, Z., & var. (2011). Suppressive effect of pectic polysaccharides from Cucurbita pepo L. Fitoterapia, 82, 357-364 53.
Qian, Z. G. (2014). Cellulase-assisted extraction of polysaccharides from Cucurbita moschata and their antibacterial activity. Carbohydrate Polymers, 101, 432–434.
Simpson, R., & Moris, G. A. (2014). The anti-diabetic potential of polysaccharides extracted from members of the cucurbit family: A review. Bioactive Carbohydrates and Dietary Fibre, 3, 106–114.
Song, Y., Yang, Y., Zhang, Y., Duan, L., Zhou, C., Ni, Y., Liao, X., Li, Q., & Hu, X. (2013). Effect of acetylation on antioxidant and cytoprotective activity of polysaccharides isolated from pumpkin (Cucurbita pepo, lady godiva. Carbohydrate Polymers, 98, 686–691.
Song, Y., Zhang, Y., Zhou, T., Zhang, H., Hu, X., & Li, Q. (2012). A preliminary study of monosaccharide composition and α-glucosidase inhibitory effect of polysaccharides from pumpkin (Cucurbita moschata) fruit. International Journal of Food Science and Technology, 47, 357–361.
Sun, J., Yin, G., Zhang, H., Chen, L., & Hu, C. (2011a). Extraction of polysaccharides from pumpkin by ultrasonic method and its primary antioxidant activities research. Advanced Materials Research, 183–185, 1970-1974 52.
Sun, J., Yin, G., Zhang, H., Chen, L., & Hu, C. (2011b). Extraction of polysaccharides from pumpkin by ultrasonic method and it’s primary antioxidant activities research. Advanced Materials Research, 183–185, 1970–1979.
Villares, A. (2014). In: Polysaccharides – Natural Fibres in Food and Nutrition (pp. 171–206).
Wang, X., Zhang, L. S., & Dang, L. L. (2012). Inhibitory effect of polysaccharides from pumpkin on advanced glycation end-products formation and aldose reductase activity. Food Chemistry, 130, 821–825.
Wu, H., Zhu, J., Diao, W., & Wang, C. (2014). Ultrasound-assisted enzymatic extraction and antioxidant activity of polysaccharides from pumpkin (Cucurbita moschata. Carbohydrate Polymers, 113, 314–324.
Xianzhe, Z., Fangping, Y., Chenghai, L., & Xiangwen, X. (2011). Effects of process parameters of microwave assisted extraction (MAE) on polysaccharides yield from pumpkin. Journal of Northeast Agricultural University, 18, 79–86.
Yadav, M., Jain, S., Tomar, R., Prasad, G. B. K. S., & Yadav, H. (2010). Medicinal and biological potential of pumpkin: An updated review. Nutrition Research Reviewers, 23, 184–190.
Yang, L., & Zhang, L. M. (2009). Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources. Carbohydrate Polymers, 76, 349–361.
Yang, X., Zhao, Y., & You, L. (2007). Chemical composition and antioxidant activity of an acidic polysaccharide extracted from Cucurbita moschata Duchesne ex Poiret. Journal of Agricultural and Food Chemistry, 55, 4684–4690.
Yoo, S. H., Lee, B. H., Lee, H., Bae, I. Y., Lee, H. G., Fishman, M. L., Chan, H. K., Savary, B. J., & Hotchkiss, A. T. (2012). Structural Characteristics of Pumpkin Pectin Extracted by Microwave Heating. Journal of Food Science, 77, 1169–1173.
Zhang, G., Su, D., Zhang, Y., Jin, H., Chen, P., Zhu, L., Wang, W., & Wang, G. (2014). The hypoglycemic effect of thepumpkin polysaccharide to the different diabetic model mice. Journal of Chinese Institute of Food Science and Technology, 14, 23–27.
Zhang, Y., Chen, P., Yu. Zhang, H. J., Zhu, L., Li, J., & Yao, H. (2013). Effects of polysaccharide from pumpkin on biochemical indicator and pancreatic tissue of the diabetic rabbits. International Journal of Biological Macromolecules, 62, 574–581.
Zhao, X. H., Qian, L., Yin, D. L., & Zhou, Y. (2014). Hypolipidemic effect of the polysaccharides extracted from pumpkin by cellulase-assisted method on mice. International Journal of Biological Macromolecules, 64, 137–138.
Znen, Y. K. (2005). Study on extraction and purification of pumpkin polysaccharide and its characterization.

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