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Originalan naučni rad– Original scientific paper

CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF PEPPERMINT ESSENTIAL OIL (Mentha piperita L.)

By
Miloš Nikolić ,
Miloš Nikolić

Institute for Biological Research ”Siniša Stanković, Belgrade, Serbia

Jasmina Glamočlija ,
Jasmina Glamočlija

Institute for Biological Research ”Siniša Stanković, Belgrade, Serbia

Ana Ćirić ,
Ana Ćirić

Institute for Biological Research ”Siniša Stanković, Belgrade, Serbia

Tatjana Marković ,
Tatjana Marković

Institute for Medicinal Plant Research ”dr Josif Pančić”, Belgrade, Serbia

Dejan Marković ,
Dejan Marković

Department of Pediatric and Preventive Dentistry, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia

Tamara Perić ,
Tamara Perić

Department of Pediatric and Preventive Dentistry, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia

Marina Soković
Marina Soković

Institute for Biological Research ”Siniša Stanković”, Belgrade, Serbia

Abstract

The aim of this study was to investigate the chemical composition and antimicrobial activity of essential oils of peppermint Mentha piperita L. GC / MS techniques confirmed the presence of the 48 components of which menthol (35.57 %) and menthone (22.50 %) were the most abundant. Antimicrobial activity, ie the minimum inhibitory and minimum bactericidal / fungicidal (MIC, MBC/MFC) concentrations were obtained using the mikordilution method against pathogenic microorganism isolated from the oral cavity (8 bacteria and 58 Candida sp.) and referent strains. The essential oil of peppermint showed good antimicrobial activity with MIC from 0.63 to 5 mg / ml and 0.13 to 0.5 for bacteria and fungi and MBC 1.25 to 10 mg / ml , ie. MFC 0.5-1 mg / ml. Compared to Hexoral®, peppermint essential oil has a very strong antimicrobial potential. The results of these tests give a new value, which will enrich the knowledge of peppermint oil od presented chemical composition, opens the door for further research towards its use in dentistry and as well in prevention and treatment of various diseases caused by tested pathogens.

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