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Stručni rad – Professional paper

QUALITY TESTINGOF CHAMOMILEESSENTIAL OIL Chamomillarecutita(L.)Rausch.,VARIETY BANATSKA, IN COMPARISON TO REQUIREMENTS OF THE EUROPEAN PHARMACOPOEIA AND ISO STANDARD

By
Katarina Šavikin ,
Katarina Šavikin

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Nebojša Menković ,
Nebojša Menković

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Mihailo Ristić ,
Mihailo Ristić

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Ivana Arsić ,
Ivana Arsić

Department of Pharmacy, Faculty of Medicine, University of Nis , Niš , Serbia

Gordana Zdunić ,
Gordana Zdunić

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Sofija Đorđević ,
Sofija Đorđević

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Sofija Ćujić ,
Sofija Ćujić

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Dejan Pljevljakušić
Dejan Pljevljakušić

Institute for Medicinal Plant Reasearch „Dr Josif Pančić “ , Belgrade , Serbia

Abstract

Essential oil of chamomile [Chamomilla recutita (L.)Rausch.,syn. Matricariachamomilla L., Asteraceae], also known as oil of German or Hungarian chamomile, is obtained by steam distillation of fresh (or partially dried) flowersand stems. Depending on various factors, essential oil yield ranges from 0.3 to 1.0%. The oil is usually clear, blue, viscous liquid, with intense, heavy scent of chamomile herbal and bitter-aromatic flavor. The essential oil contains a variety of pharmacologically active substances, where α-bisabolol, its oxides, chamazulene spiroethers and certainly the most important. It is used in the production and standardization of certain pharmaceutical and cosmetic products. This paper presents the results of the chemical analysis of essential oils of chamomile, variety Banatska, received at the facility for the extraction and distillation of the Institute for Medicinal Plant Research "Dr Josif Pančić". The oil analysis is carried out using gas chromatography (GC/ FID) and gas chromatography / mass spectrometry (GC/ MS). The essential oil had the highest content of trans-β-farnesene (46.69%), while the α-bisabolol and its oxides, azulene and chamazulene were found to be more than 1%. Itwas fortified that the chemical profile of the oil is not liable to Ph Eur 6.0. nor ISO 19332 standard.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 

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