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This study was aimed to compare the efficiency of silymarin extraction from Silybi mariani fructus using different extraction methods. Maceration, percolation, extraction in a water bath, and ultrasonicassisted extraction have been performed with 60% ethanol. Extracts were analyzed using UV/Vis and HPLC techniques. Our results showed that the highe...

By Sofija Đorđević, Teodora Janković, Milica Mihailović

Due to its high content of phenolics, black chokeberry has been proposed as a health-promoting material, especially use of chokeberry extract as a food or pharmaceuticals. Chokeberry extract was spray-dried using gum Arabic as a carrier. The optimal conditions for the efficient microencapsulation of chokeberry extract using spray-drying technique h...

By Nada Čujić-Nikolić, Nemanja Stanisavljević, Katarina Šavikin, Ana Kalaušević, Viktor Nedović, Dubravka Bigović, Teodora Janković

In this study, water and various concentrations of ethanol in water (30 %, 50 %, 70 %, and 90 %) were used as a solvent in the extraction of two different samples of hemp (Cannabis sativa L.). The extraction yield, total phenols content, total flavonoids content, antioxidant activity, and reductive capacity were determined in the obtained extracts....

By Zorica Drinić, Senka Vidović, Jelena Vladić, Anamarija Koren, Biljana Kiprovski, Vladmir Sikora

Biological activities of Sorbus aucuparia L. leaves extract was tested in our study. Antineurodegenerative activity was evaluated by acetylcholinesterase (AChE) and tyrosinase (TYR) inhibitory activity assays while antioxidant activity was by tested using four different assays. In all antioxidant test we noticed concentration dependent activity of ...

By Katarina Šavikin, Gordan Zdunić, Ana Alimpić, Dubravka Bigović, Dejan Pljevljakušić, Sonja Duletić-Laušević

Polyphenols are secondary plant metabolites with proven antioxidant activity, which have an important part in prevention of many diseases. Pineapple (Ananas comosus (L.) Merr. family Bromeliaceae) is a plant native to Central America. Pineapple fruit is the most common part of plant used in both, nutrition and traditional medicine, but other parts ...

By Miljana Jovanović, Milica MIlutinović, Milica Kostić, Nemanja Kitić, Suzana Brankovič, Dušanka Kitič

Medicinal plant extracts have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extracts of ten different medicinal plants prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in different concentrations have been examined for anti-norovirus activity. The reduction of norovirus &g...

By Ivana Živković, Katarina Šavikin, Gordana Zdunić, Jelena Živković, Dubravka Bigović, Nebojša Menković, Dragoslav Radin

Raphanus sativus L. (Brassicaceae) is an edible plant, whose root is consumed all over the world. The objective of this study was to test antibacterial potential of R. sativus ethanolic extract on 12 pathogenic bacteria including multiresistant bacterial strains and MRSA. All of the tested bacteria showed sensitivity to the antibacterial effect of ...

By Dejan Stojković, Marija Smiljković, Miloš Nikolić, Jelena Živković, Marina Soković

Biologically active compounds from plants have attracted great interest due to their affordability, effectiveness and low toxicity. Herbal extracts provide an infinite resource of raw materials for pharmaceutical, cosmetic and food industry. Unfortunately, use of the valuable natural compounds can be limited by their low bioavailability, volatiliza...

By Jelena Mudrić, Svetlana Ibrić, Jelena Đuriš

Lichens represent a promising source of antimicrobial, cytotoxic and antioxidant agents. Their great pharmacological potential lies in the fact that they represent specific symbiotic organisms and thus possess natural roles allowing them to be highly adaptable to different environmental conditions. On the other hand, stated biological activities of...

By Ana Zugić, Vanja Tadić, Tatjana Kundaković, Snežana Savić

This doctoral dissertation was focused on the optimization of the extraction parameters to achieve the maximum yield of phenolic compounds in the Urtica dioica L. leaf extracts. The extract with the highest content of phenolic compounds was tested in the model of experimental hypertension to determine its effects on oxidative and hemodynamic status...

By Una-Jovana Vajić