Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes
Steppe peony (Paeonia tenuifolia L., Paeoniaceae) is a perennial, herbaceous plant species which has been widely known for its medicinal use. This study is aimed at the development of P. tenuifolia petal dry methanolic extract-loaded liposomes and the determination of their antioxidant activity. The liposomes were prepared with three different phos...
By Natalija Cutovic, Tatjana Marković, Ana Žugić, Petar Batinic, Branko Bugarski, Aleksandra Jovanović
Developed and validated HPLC method for simultaneous analysis of key flavonoids and phenolcarboxylic acids in the hawthorn-based cardiotonic Forticor®
Relatively simple, but very reliable, one-step qualitative/quantitative HPLC analysis of four key flavonoids, and a phenolcarboxylic acid, has been introduced. For substrate/sample preparations, either triple percolations, using 70% ethanol-water (V/V), or/and ultrasonic bath methanol extractions, were carried out to obtain the desired isolates yi...
By Vanja Tadic, Dragica Bojovic, Goran Marković, Ivana Nešić, Ana Žugić
Microbiological quality and efficacy of preservatives in marigold-based skin care products
The microbiological stability of cosmetic products is crucial, especially in products with high water content, such as creams. Therefore, preservatives are used in order to protect consumers from harmful pathogens that would otherwise invade the cosmetics. Despite their function, the addition of preservatives can be considered controversial in the ...
By Tatjana Stević, Nemanja Krgovic, Jelena Mudrić, Nada Cujic Nikolic, Ana Žugić, Dubravka Bigović, Tea Ganić, Katarina Šavikin
Lady’s mantle (Alchemilla vulgaris L., Rosaceae): A review of traditional uses, phytochemical profile, and biological properties
Lady’s mantle (Alchemilla vulgaris L. syn. Alchemilla xanthochlora Rothm., Rosaceae) has been commonly used in folk medicine to heal inflammations in the mouth, bleeding of the nose, furuncules, gynaecological (menorrhagia and dysmenorrhoea), and gastrointestinal disorders. Although therapeutic indications for Lady’s mantle are non-specific diarrho...
By Vanja Tadić, Nemanja Krgović, Ana Žugić
Variation of parthenolide and phenolic compounds content in different parts of Tanacetum parthenium (L.) Schulz Bip., Asteraceae during 18 months storage
Tanacetum parthenium (L.) Schulz Bip., Asteraceae (feverfew), being a medicinal plant with a long tradition in European folk medicine, has been used to treat headache, fever, rheumatism, asthma, stomach pains, and other conditions related to inflammation. Although feverfew is often used for migraine headaches, numerous literature data stated the in...
By Vladan Tadić, Jelena Živković, Dubravka Bigović, Ana Žugić
Chemical composition and biological activities of the extracts and secondary metabolites of lichens belonging to the genus Usnea, Parmeliaceae
Lichens represent a promising source of antimicrobial, cytotoxic and antioxidant agents. Their great pharmacological potential lies in the fact that they represent specific symbiotic organisms and thus possess natural roles allowing them to be highly adaptable to different environmental conditions. On the other hand, stated biological activities of...
By Ana Zugić, Vanja Tadić, Tatjana Kundaković, Snežana Savić
Preliminary safety estimate of cosmetic anti-age creams with chokeberry extract, using in vivo bioengineering techniques
Potential of anti-age cosmetic line, day and night creams was evaluated using noninvasive measurements of the appropriate skin biophysical parameters in a 24-h in vivo study under occlusion. Thirty one healthy female volunteers were involved in the study. Electrical capacitance (EC), transepidermal water loss (TEWL), erythema index (EI) were evalua...
By Nada Čujić, Ana Žugić, Gordana Zdunić, Katarina Šavikin