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Research Article
Published: 25.12.2018.
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https://doi.org/10.5937/leksir1838031Z

Antiviral activity of medicinal plants extracts against foodborne norovirus

By
Ivana Živković ,
Ivana Živković

Institute for Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade, Serbia

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Katarina Šavikin ,
Katarina Šavikin

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

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Gordana Zdunić ,
Gordana Zdunić

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

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Jelena Živković ,
Jelena Živković

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

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Dubravka Bigović ,
Dubravka Bigović

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

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Nebojša Menković ,
Nebojša Menković

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

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Dragoslav Radin
Dragoslav Radin
Contact Dragoslav Radin

Institute for Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade, Serbia

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Abstract

Medicinal plant extracts have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extracts of ten different medicinal plants prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in different concentrations have been examined for anti-norovirus activity. The reduction of norovirus >1 log10 genome equivalents has been obtained with 1 mg/mL of Aronia melanocarpa leaf extract, dried wine Prokupac and Hypericum perforatum extract. Some of the observed extracts i.e. Hypericum perforatum, Aronia melanocarpa fruit extract and Punica granatum peel extract showed better activity when dissolved in 30% ethanol with 5% DMSO. All results of anti-noroviral activity of tested extracts which achieved <0.5 log10 genome equivalents were considered as not effective.
 


 

Keywords:

Human norovirus,
medicinal plant extract,
antiviral activity

References

Akram, M., Tahir, I. M., Shah, S. M. A., Mahmood, Z., Altaf, A., Ahmad, K., Munir, N., Daniyal, M., Nasir, S., & Mehboob, H. (2018). Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review. Phytotherapy Research, 32(5), 811–822.
Alimentarius, C. (2012). CAC/GL 79-2012 guidelines on the application of general principles of food hygiene to the control of viruses in food.
Braga, L., Shupp, J., Cummings, C., Jett, M., Takahashi, J., Carmo, L., Chartone-Souza, E., & Nascimento, A. (2005). Pomegranate extract inhibits Staphylococcus aureus growth and subsequent enterotoxin production. Journal of Ethnopharmacology, 96(1–2), 335–339.
Carvalho Meirelles, G., Bridi, H., Rates, S. M. K., & Poser, G. L. (2019). Southern Brazilian Hypericum Species, Promising Sources of Bioactive Metabolites. Studies in Natural Products Chemistry, 59, 491–507.
D’Souza, D. H., & E.F.S.A./E.C.D.C. (2014). Phytocompounds for the control of human enteric viruses. Current Opinion in Virology, 4(12), 44–49.
El-Senousy, W. M., El-Gamal, M. S., Mousa, A. A. E.-B., ElHawary, S. E.-S., Kamel, M. M., Fathi, M. N., & El-Mahdy, E.-M. M. (2014). Effect of Chlorine on Noroviruses. Rotaviruses and Hepatitis E Virus in Drinking Water, World Applied Sciences Journal, 32(11), 2206–2212.
Jaykus, L., D’Souza, D., & Moe, C. (2013). Foodborne viruses. In Food Microbiology Fundamentals and Frontiers.
Kingsley, D. H., Vincent, E. M., Meade, G. K., Watson, C. L., & Fan, X. (2014). Inactivation of human norovirus using chemical sanitizers. International Journal of Food Microbiology, 171, 94–99.
Oh, M., Lee, J.-H., Bae, S. Y., Seok, J. H., Kim, S., Chung, Y. B., Han, K. R., Kim, K. H., & Chung, M. S. (2015). Protective effects of red wine and resveratrol for foodborne virus surrogates. Food Control, 47, 502–509.
Papapanagiotou, E. (2017). Foodborne Norovirus State of Affairs in the EU Rapid Alert System for Food and Feed. Veterinary Sciences, 4(4), 61.
Park, S., Kim, J. I., Lee, I., Lee, S., Hwang, M.-W., Bae, J.-Y., Heo, J., Kim, D., Han, S.-Z., & Park, M.-S. (2013). Aronia melanocarpa and its components demonstrate antiviral activity against influenza viruses. Biochemical and Biophysical Research Communications, 440(1), 14–19.
Radin, D., & D’Souza, D. H. (2011). Simple and Rapid Detection of Human Norovirus from Produce Using SYBR Green I-based Real-time RT-PCR. Food and Environmental Virology, 3(3–4), 121–129.
Rocha-Pereira, J., Dycke, J., & Neyts, J. (2016). Norovirus genetic diversity and evolution: implications for antiviral therapy. Current Opinion in Virology, 20, 92–98.

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Vol 38, Issue 1, 2018
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