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Research Article

Antiviral activity of medicinal plants extracts against foodborne norovirus

By
Ivana Živković ,
Ivana Živković

Institute for Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade, Serbia

Katarina Šavikin ,
Katarina Šavikin

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

Gordana Zdunić ,
Gordana Zdunić

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

Jelena Živković ,
Jelena Živković

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

Dubravka Bigović ,
Dubravka Bigović

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

Nebojša Menković ,
Nebojša Menković

Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia

Dragoslav Radin
Dragoslav Radin
Contact Dragoslav Radin

Institute for Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade, Serbia

Abstract

Medicinal plant extracts have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extracts of ten different medicinal plants prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in different concentrations have been examined for anti-norovirus activity. The reduction of norovirus >1 log10 genome equivalents has been obtained with 1 mg/mL of Aronia melanocarpa leaf extract, dried wine Prokupac and Hypericum perforatum extract. Some of the observed extracts i.e. Hypericum perforatum, Aronia melanocarpa fruit extract and Punica granatum peel extract showed better activity when dissolved in 30% ethanol with 5% DMSO. All results of anti-noroviral activity of tested extracts which achieved <0.5 log10 genome equivalents were considered as not effective.
 


 

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