Enzyme inhibitors as controllers of neurodegenerative diseases: An update of in vitro effects of medicinal plants
Considering the increase of the elderly population in recent years, the growing prevalence of age-related neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD) and Parkinson’s disease (PD), has become one of the leading healthcare problems. Currently, available therapies for AD and PD are still limited, while medicinal p...
By Ana Alimpić-Aradski, Mariana Oalđe-Pavlović, Smiljana Janković, Petar D.Marin, Sonja Duletić-Laušević
In vitro and in silico prediction of antineurodegenerative properties of Helichrysum plicatum flower extract
This study aimed to assess the antineurodegenerative and antioxidant activity of Helichrysum plicatum flower extract, as well as to identify extract ingredients with acceptable pharmacokinetic parameters such as gastrointestinal absorption, blood-brain barrier permeation, and P-glycoprotein-mediated effusion for optimal therapeutic brain exposure. ...
By Miloš Jovanović, Zorica Drinić, Dubravka Bigović, Ana Alimpić-Aradski, Sonja Duletić-Laušević, Katarina Šavikin
In vitro evaluation of antioxidant, antineurodegenerative and antidiabetic activities of Ocimum basilicum L., Laurus nobilis L. leaves and Citrus reticulata Blanco peel extracts
<i>Ocimum basilicum<i> (sweet basil) and <i>Laurus nobilis</i> (bay leaves or laurel) have been used in traditional medicine for centuries, and also extensively employed as spices for adding aroma and flavor to various food products. <i>Citrus reticulata</i> (mandarin) is mainly used in food industry for ju...
By Sonja Duletić-Laušević, Mariana Oalđe, Ana Alimpić-Aradski