Development of gastroretentive floating granules with gentian root extract by hot-melt granulation
The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of the solid pharmaceutical forms. Gentiopicroside, as a dominant secoiridoid in the GRE, has a sho...
By Jelena Mudrić, Mirjana Pajić, Dubravka Bigović, Jelena Đuriš
Double emulsions (W/O/W emulsions): Encapsulation of Plant Biactives
This article describes the preparation, characterization, and application of W/O/W emulsions, with emphasis on the encapsulation of plant bioactives. The main limitations preventing commercialization of double emulsions with plant bioactive substances, used for the preparation of food, nutraceuticals and pharmaceuticals for oral administration, are...
By Jelena Mudrić, Katarina Šavikin, Svetlana Ibrić, Jelena Đuriš
Microencapsulation methods for plants biologically active compounds - a review
Biologically active compounds from plants have attracted great interest due to their affordability, effectiveness and low toxicity. Herbal extracts provide an infinite resource of raw materials for pharmaceutical, cosmetic and food industry. Unfortunately, use of the valuable natural compounds can be limited by their low bioavailability, volatiliza...
By Jelena Mudrić, Svetlana Ibrić, Jelena Đuriš